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宫内节育器是否为输卵管卵巢脓肿患者保守治疗失败的危险因素?一项观察性回顾性研究。

Is intrauterine device a risk factor for failure of conservative management in patients with tubo-ovarian abscess? An observational retrospective study.

作者信息

Kapustian Victoria, Namazov Ahmet, Yaakov Odeliya, Volodarsky Michael, Anteby Eyal Y, Gemer Ofer

机构信息

Department of Obstetrics and Gynecology, Faculty of Health Sciences, Barzilai Medical Center, Ben-Gurion University of Negev, HaHistadrut Street 2, Ashkelon, Israel.

出版信息

Arch Gynecol Obstet. 2018 May;297(5):1201-1204. doi: 10.1007/s00404-018-4690-z. Epub 2018 Feb 24.

Abstract

PURPOSE

Tubo-ovarian abscess (TOA) is a serious and potentially life-threatening complication of pelvic inflammatory disease (PID). TOA formation may be an uncommon, but serious complication associated with the use of an intrauterine device (IUD). While the majority of TOA respond to antibiotic therapy, in approximately 25% of cases surgery or drainage is indicated. In the present study, we compared the failure rate of conservative management in patients with and without IUD, who were admitted with a diagnosis of TOA.

METHODS

In this retrospective case-control study, 78 women were diagnosed with TOA. All patients were treated initially by broad-spectrum intravenous antibiotics. The failure of conservative management after 72 h was followed by surgical intervention.

RESULTS

The patients were divided into two groups: 24 patients were IUD-carriers, and 54 did not use IUD. There was no significant difference in surgical intervention rate between IUD group (50%) and no-IUD group (43%), p = 0.32. The WBC count was significantly higher in IUD-carriers diagnosed with TOA than in patients without IUD (16.5 ± 6.6 vs. 13.1 ± 4.6, p = 0.001). The patients with IUD had significantly larger abscesses as revealed by ultrasound than patients without IUD (61.6 ± 21.4 vs. 49.6 ± 20.6 mm, p = 0.02).

CONCLUSION

The surgical intervention rate in TOA patients with and without IUD was similar.

摘要

目的

输卵管卵巢脓肿(TOA)是盆腔炎性疾病(PID)的一种严重且可能危及生命的并发症。TOA的形成可能是使用宫内节育器(IUD)相关的一种不常见但严重的并发症。虽然大多数TOA对抗生素治疗有反应,但在约25%的病例中需要手术或引流。在本研究中,我们比较了诊断为TOA且带或不带IUD的患者保守治疗的失败率。

方法

在这项回顾性病例对照研究中,78名女性被诊断为TOA。所有患者最初均接受广谱静脉抗生素治疗。72小时后保守治疗失败则进行手术干预。

结果

患者分为两组:24名患者携带IUD,54名未使用IUD。IUD组(50%)和无IUD组(43%)的手术干预率无显著差异,p = 0.32。诊断为TOA的IUD携带者的白细胞计数显著高于未使用IUD的患者(16.5±6.6对13.1±4.6,p = 0.001)。超声显示,携带IUD的患者脓肿明显大于未使用IUD的患者(61.6±21.4对49.6±20.6mm,p = 0.02)。

结论

带或不带IUD的TOA患者的手术干预率相似。

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