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宫内节育器的存在及其他因素对输卵管卵巢脓肿治疗效果的影响。

The effect of intrauterine device presence and other factors in medical treatment success of tuboovarian abscess.

机构信息

University of Health Science, Ministry of Health Ankara City Hospital, Ankara, Turkey.

Department of Oncology, University of Health Science, Ministry of Health Ankara City Hospital, Ankara, Turkey.

出版信息

J Gynecol Obstet Hum Reprod. 2021 May;50(5):101983. doi: 10.1016/j.jogoh.2020.101983. Epub 2020 Nov 12.

Abstract

BACKGROUND

To identify the epidemiologic and clinical risk factors associated with failed response to medical treatment in tuboovarian abscess (TOA) patients and whether there is a relationship between the presence of intrauterine device (IUD), duration of use and medical treatment success or not.

METHODS

For this study, the medical records of patients diagnosed with TOA and hospitalized in an 8-year period were analyzed retrospectively. The presence of TOA and IUD was confirmed ultrasonographically in all patients. Parenteral antibiotic treatment was initiated as the first step. Patients who did not improve with this medical treatment underwent surgery. Patients who recovered with medical treatment were defined as the successful group, while those who underwent surgery after medical treatment failure were recorded as the failed group.

RESULTS

There were 37 patients in successful group and 87 patients in failed group. The mean age, parity, white blood count, TOA size, duration of IUD use, rate of multigravida and multiparity were higher in the failed group. Logistic regression analysis revealed that presence of multiparity, TOA size and the duration of IUD use were significant independent factors in predicting medical treatment success of TOA. The best cut-off value for TOA size was 4.5 cm and for duration of IUD use was 5.5 years in the Receiver Operating Characteristic curve analysis.

CONCLUSION

The presence of long-term IUD use, increased TOA size, and multiparity were found to be risk factors related to the failure of medical treatment in TOA cases.

摘要

背景

确定与输卵管卵巢脓肿(TOA)患者药物治疗失败相关的流行病学和临床风险因素,以及宫内节育器(IUD)的存在、使用时间与药物治疗成功与否之间是否存在关系。

方法

在这项研究中,回顾性分析了 8 年内因 TOA 住院的患者的病历。所有患者均经超声证实存在 TOA 和 IUD。首先给予静脉内抗生素治疗。对药物治疗无效的患者进行手术。经药物治疗后痊愈的患者定义为成功组,而药物治疗失败后接受手术的患者记录为失败组。

结果

成功组有 37 例患者,失败组有 87 例患者。失败组的平均年龄、产次、白细胞计数、TOA 大小、IUD 使用时间、多胎妊娠率和多产率均较高。Logistic 回归分析显示,多产、TOA 大小和 IUD 使用时间是预测 TOA 药物治疗成功的独立显著因素。TOA 大小的最佳截断值为 4.5cm,IUD 使用时间的最佳截断值为 5.5 年。

结论

长期使用 IUD、TOA 增大和多产被认为是 TOA 患者药物治疗失败的相关风险因素。

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