编码人PGP 9.5蛋白的cDNA的分子克隆。一种用于神经元和神经内分泌细胞的新型细胞质标志物。
Molecular cloning of cDNA coding for human PGP 9.5 protein. A novel cytoplasmic marker for neurones and neuroendocrine cells.
作者信息
Day I N, Thompson R J
出版信息
FEBS Lett. 1987 Jan 5;210(2):157-60. doi: 10.1016/0014-5793(87)81327-3.
PMID:2947814
Abstract
The co-ordinate sequencing of the human neuronal and neuroendocrine marker protein PGP 9.5 and its cDNA is described. The cDNA encodes the complete protein (212 amino acids), and the 340 nucleotide 3'-noncoding region including the polyadenylation signal, indicating an mRNA slightly larger than 1 kb in size. Protein sequencing of 50% of PGP 9.5 confirms the deduced protein sequence.
摘要
本文描述了人类神经元和神经内分泌标志物蛋白PGP 9.5及其cDNA的坐标测序。该cDNA编码完整蛋白（212个氨基酸），以及包含多聚腺苷酸化信号的340个核苷酸的3'非编码区，表明mRNA大小略大于1 kb。对PGP 9.5 50%的蛋白测序证实了推导的蛋白序列。
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