Wistermayer Paul R, McIlwain Wesley R, Ieronimakis Nicholas, Rogers Derek J
1 Madigan Army Medical Center, Tacoma, Washington, USA.
Ann Otol Rhinol Laryngol. 2018 Apr;127(4):275-281. doi: 10.1177/0003489418759361. Epub 2018 Feb 24.
Validate an accurate and reproducible method of measuring the cross-sectional area (CSA) of the upper airway.
This is a prospective animal study done at a tertiary care medical treatment facility. Control images were obtained using endotracheal tubes of varying sizes. In vivo images were obtained from various timepoints of a concurrent study on subglottic stenosis. Using a 0° rod telescope, an instrument was placed at the level of interest, and a photo was obtained. Three independent and blinded raters then measured the CSA of the narrowest portion of the airway using open source image analysis software.
Each blinded rater measured the CSA of 79 photos. The t testing to assess for accuracy showed no difference between measured and known CSAs of the control images ( P = .86), with an average error of 1.5% (SD = 5.5%). All intraclass correlation (ICC) values for intrarater agreement showed excellent agreement (ICC > .75). Interrater reliability among all raters in control (ICC = .975; 95% CI, .817-.995) and in vivo (ICC = .846;, 95% CI, .780-.896) images showed excellent agreement.
We validate a simple, accurate, and reproducible method of measuring the CSA of the airway that can be used in a clinical or research setting.
验证一种准确且可重复的测量上气道横截面积（CSA）的方法。
这是一项在三级医疗设施中进行的前瞻性动物研究。使用不同尺寸的气管导管获取对照图像。体内图像取自一项关于声门下狭窄的同期研究的不同时间点。使用0°杆状望远镜，将仪器置于感兴趣的水平位置并拍摄照片。然后，三名独立且不知情的评估者使用开源图像分析软件测量气道最窄部分的CSA。
每位不知情的评估者测量了79张照片的CSA。用于评估准确性的t检验显示，对照图像的测量CSA与已知CSA之间无差异（P = 0.86），平均误差为1.5%（标准差 = 5.5%）。所有评估者内部一致性的组内相关系数（ICC）值均显示出极佳的一致性（ICC > 0.75）。对照图像（ICC = 0.975；95%置信区间，0.817 - 0.995）和体内图像（ICC = 0.846；95%置信区间，0.780 - 0.896）中所有评估者之间的评分者间可靠性均显示出极佳的一致性。
我们验证了一种简单、准确且可重复的测量气道CSA的方法，可用于临床或研究环境。
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