Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
J Thorac Cardiovasc Surg. 2018 Jun;155(6):2429-2436. doi: 10.1016/j.jtcvs.2017.12.126. Epub 2018 Feb 1.
Heart valve surgery guidelines suggest that tricuspid valve annuloplasty may be beneficial in patients with a tricuspid annulus (TA) ≥40 mm even in the absence of functional tricuspid regurgitation (TR) at the time of surgery for left-sided valve lesions (class 2a). Given the broad spectrum of degenerative diseases that affect the atrioventricular valves, we hypothesize that this measurement might not be predictive of TR after mitral valve (MV) repair.
The diameter of the TA was measured preoperatively in a cohort of 312 consecutive patients who had isolated MV repair for degenerative diseases. The mean TA diameter was 36 mm (95% confidence interval [CI], 35-37 mm). TA ≥40 mm was present in 80 patients. The median duration of echocardiographic follow-up was 6.7 years (interquartile range, 5.4-8.4 years), and was 100% complete. The main study endpoint was postoperative TR of moderate or greater degree.
Thirty patients had new or persistent TR at some point during follow-up. The probability of postoperative TR at 7 years was 6.6% (95% CI, 4.6%-9.4%) for all patients, 6.8% (95% CI, 4.6%-10.4%) for TA <40 mm, and 6.0% (95% CI, 2.9%-12.2%) for TA ≥40 mm. Preoperative TA diameter was not associated with the odds of postoperative TR in either the univariable or multivariable regression models. In these analyses, preoperative TR was the strongest predictor of postoperative TR.
TA ≥40 mm is not predictive of the development of postoperative TR after MV repair for degenerative diseases.
心脏瓣膜手术指南建议,即使在左侧瓣膜病变(IIa 类)手术时不存在功能性三尖瓣反流(TR),三尖瓣瓣环(TA)≥40mm 的患者也可能从三尖瓣瓣环成形术中获益。鉴于影响房室瓣的退行性疾病谱广泛,我们假设该测量方法可能无法预测二尖瓣(MV)修复后的 TR。
在连续 312 例因退行性疾病接受单纯 MV 修复的患者中,术前测量 TA 的直径。TA 的平均直径为 36mm(95%置信区间 [CI],35-37mm)。80 例患者的 TA≥40mm。中位超声心动图随访时间为 6.7 年(四分位间距,5.4-8.4 年),随访率为 100%。主要研究终点为术后中重度或以上 TR。
30 例患者在随访过程中的某个时间点出现新的或持续性 TR。所有患者术后 7 年 TR 的概率为 6.6%(95%CI,4.6%-9.4%),TA<40mm 者为 6.8%(95%CI,4.6%-10.4%),TA≥40mm 者为 6.0%(95%CI,2.9%-12.2%)。在单变量和多变量回归模型中,术前 TA 直径与术后 TR 的可能性均无关。在这些分析中,术前 TR 是术后 TR 的最强预测因素。
TA≥40mm 并不能预测退行性疾病患者 MV 修复术后 TR 的发生。