Özgür Gökhan, Beyan Cengiz
Gulhane Training and Research Hospital, Department of Hematology, Ankara, Turkey.
TOBB University of Economics and Technology, Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey.
Transfus Apher Sci. 2018 Feb;57(1):13-15. doi: 10.1016/j.transci.2018.02.008. Epub 2018 Feb 20.
Catastrophic thrombotic syndrome is characterized by occurrence of several thromboembolic occlusions which affect a variety of vascular beds over a short period of time. Catastrophic Antiphospholipid syndrome (CAPS) (1%) is regarded as a rare but severe variant of Antiphospholipid Syndrome. Treatment with anticoagulants, steroids and therapeutic plasma exchange has been shown to give the best results. However, to treat CAPS, the best substitute for plasma is still a debatable issue because there are no standard methods.
灾难性血栓形成综合征的特征是在短时间内出现多个血栓栓塞性闭塞，影响多种血管床。灾难性抗磷脂综合征（CAPS）（1%）被认为是抗磷脂综合征的一种罕见但严重的变体。已证明使用抗凝剂、类固醇和治疗性血浆置换进行治疗可取得最佳效果。然而，由于没有标准方法，治疗CAPS时，血浆的最佳替代品仍是一个有争议的问题。
