宫内人工授精的复兴：循证数据改变了局面。
The revival of intrauterine insemination: evidence-based data have changed the picture.
作者信息
Ombelet Willem
机构信息
Editor-in-Chief.
Genk Institute for Fertility Technology, ZOL Hospitals, Schiepse Bos 6, 3600 Genk, Belgium.
出版信息
Facts Views Vis Obgyn. 2017 Sep;9(3):131-132.
Abstract
According to a number of high quality studies intrauterine insemination (IUI) with homologous semen should be the first choice treatment in case of unexplained and moderate male factor subfertility. IVF and ICSI are clearly over-used in this selected group of infertile couples. The limited value of IUI in infertility treatment as mentioned in the 2013 NICE guidelines was surely a premature statement and should be adapted to the actual literature. More evidence-based data are becoming available on different variables influencing the success rates after IUI. It can be expected that these findings may lead to a better understanding and use of IUI in the near future.
摘要
根据多项高质量研究，对于不明原因及中度男性因素导致的亚生育情况，使用同源精液进行宫腔内人工授精（IUI）应作为首选治疗方法。在这一特定的不孕夫妇群体中，体外受精（IVF）和卵胞浆内单精子注射（ICSI）显然被过度使用。2013年英国国家卫生与临床优化研究所（NICE）指南中提到的IUI在不孕治疗中的价值有限，这肯定是一个过早的论断，应该根据实际文献进行调整。关于影响IUI成功率的不同变量，越来越多基于证据的数据正在出现。可以预期，这些研究结果可能会在不久的将来使人们对IUI有更好的理解和应用。
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