Galabov A S, Galegov G A
Acta Virol. 1978 Jul;22(4):343-51.
An analysis of the methods of testing the antiviral activity in vitro (in cell cultures) and in vivo (in experimental virus infections) is presented. The necessity of applying two-stage screening in vitro is emphasized. The chemotherapeutic viral models is in vitro testing as well as the principles of modelling of experimental viral infections are examined. Criteria for stage-by-stage assessment of the antiviral activity of the substances tested are formulated.
本文对体外（细胞培养中）和体内（实验性病毒感染中）抗病毒活性检测方法进行了分析。强调了在体外应用两阶段筛选的必要性。研究了体外化疗病毒模型以及实验性病毒感染的建模原则。制定了对受试物质抗病毒活性进行逐阶段评估的标准。
