• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

磷丙酯:一种具有抗病毒和免疫调节活性的新型药物。

Phosprenyl: a novel drug with antiviral and immunomodulatory activity.

作者信息

Danilov L L, Maltsev S D, Deyeva A V, Narovlyansky A N, Sanin A V, Ozherelkov S V, Pronin A V

机构信息

Joint-Stock Company Micro-plus, N.F. Gamaleya Research Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow, Russia.

出版信息

Arch Immunol Ther Exp (Warsz). 1996;44(5-6):395-400.

PMID:9017158
Abstract

A novel antiviral drug with immunomodulatory activity (Phosprenyl) is presented. The main active ingredient of the preparation is polyprenyl phosphates. This medicine is highly efficient against a number of viruses, including HIV in vitro, and tick-borne encephalitis and rabies viruses in the experimental models in vivo. In veterinary practice Phosprenyl is now regarded as an effective therapeutic means for treatment of canine distemper, hepatitis, enteritis, etc.

摘要

一种具有免疫调节活性的新型抗病毒药物(磷戊酯)已被提出。该制剂的主要活性成分是聚异戊二烯磷酸酯。这种药物对多种病毒具有高效性,包括体外的HIV,以及体内实验模型中的蜱传脑炎病毒和狂犬病病毒。在兽医实践中,磷戊酯现在被视为治疗犬瘟热、肝炎、肠炎等疾病的有效治疗手段。

相似文献

1
Phosprenyl: a novel drug with antiviral and immunomodulatory activity.磷丙酯:一种具有抗病毒和免疫调节活性的新型药物。
Arch Immunol Ther Exp (Warsz). 1996;44(5-6):395-400.
2
[Protective effect of a new antiviral preparation of phosprenyl in experimental tick-borne encephalitis].[磷普瑞尼新型抗病毒制剂在实验性蜱传脑炎中的保护作用]
Vopr Virusol. 2000 Jan-Feb;45(1):33-7.
3
Use of oseltamivir in the treatment of canine parvoviral enteritis.奥司他韦在犬细小病毒性肠炎治疗中的应用。
J Vet Emerg Crit Care (San Antonio). 2010 Feb;20(1):132-42. doi: 10.1111/j.1476-4431.2009.00404.x.
4
Evaluation of the efficacy and duration of immunity of a canine combination vaccine against virulent parvovirus, infectious canine hepatitis virus, and distemper virus experimental challenges.犬用联合疫苗针对强毒细小病毒、犬传染性肝炎病毒和犬瘟热病毒实验性攻毒的免疫效力及免疫持续时间评估。
Vet Ther. 2004 Fall;5(3):173-86.
5
Antiviral activity of the novel immune modulator 7-thia-8-oxoguanosine.新型免疫调节剂7-硫杂-8-氧代鸟苷的抗病毒活性
J Biol Response Mod. 1990 Feb;9(1):24-32.
6
Parvovirus infection treatment.细小病毒感染的治疗
Vet Rec. 1979;105(25-26):581.
7
[Hepatitis B virus and the inflammatory/immunologic response (II): a new opportunity for the treatment of chronic hepatitis B and a suggestion for the treatment of other persistent viral diseases].[乙型肝炎病毒与炎症/免疫反应(II):慢性乙型肝炎治疗的新机遇及对其他持续性病毒疾病治疗的建议]
Rev Esp Enferm Dig. 1998 Jul;90(7):514-22.
8
[Antiviral activity of the natural immunostimulant "Vegetan" in murine herpetic meningoencephalitis, guinea pig genital herpes, and canine parvoviral enteritis].[天然免疫刺激剂“Vegetan”对小鼠疱疹性脑膜脑炎、豚鼠生殖器疱疹和犬细小病毒肠炎的抗病毒活性]
Vopr Virusol. 1995 Mar-Apr;40(2):85-9.
9
New Approaches to the Prevention and Treatment of Viral Diseases.病毒病的预防和治疗新方法。
Arch Immunol Ther Exp (Warsz). 2021 Apr 3;69(1):10. doi: 10.1007/s00005-021-00613-w.
10
[Phosphogliv: mechanism of therapeutic action and clinical efficacy].[复方甘草酸苷:治疗作用机制与临床疗效]
Vopr Med Khim. 2002 Mar-Apr;48(2):139-53.

引用本文的文献

1
New Approaches to the Prevention and Treatment of Viral Diseases.病毒病的预防和治疗新方法。
Arch Immunol Ther Exp (Warsz). 2021 Apr 3;69(1):10. doi: 10.1007/s00005-021-00613-w.
2
Antibacterial, cytotoxic and genotoxic activity of nitrogenated and haloid derivatives of C-C and C-C polyprenol homologs.
Lipids Health Dis. 2016 Oct 10;15(1):175. doi: 10.1186/s12944-016-0345-x.
3
In Vivo and In Vitro Toxicity Evaluation of Polyprenols Extracted from Ginkgo biloba L. Leaves.从银杏叶中提取的聚戊烯醇的体内和体外毒性评估
Molecules. 2015 Dec 11;20(12):22257-71. doi: 10.3390/molecules201219839.
4
Antiviral activity of a nanoemulsion of polyprenols from ginkgo leaves against influenza A H3N2 and hepatitis B virus in vitro.银杏叶多萜醇纳米乳剂对甲型H3N2流感病毒和乙型肝炎病毒的体外抗病毒活性
Molecules. 2015 Mar 19;20(3):5137-51. doi: 10.3390/molecules20035137.
5
Plant polyisoprenoids and control of cholesterol level.植物多萜类化合物与胆固醇水平的控制。
Arch Immunol Ther Exp (Warsz). 2014 Feb;62(1):31-9. doi: 10.1007/s00005-013-0253-y. Epub 2013 Aug 31.