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磷丙酯:一种具有抗病毒和免疫调节活性的新型药物。

Phosprenyl: a novel drug with antiviral and immunomodulatory activity.

作者信息

Danilov L L, Maltsev S D, Deyeva A V, Narovlyansky A N, Sanin A V, Ozherelkov S V, Pronin A V

机构信息

Joint-Stock Company Micro-plus, N.F. Gamaleya Research Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow, Russia.

出版信息

Arch Immunol Ther Exp (Warsz). 1996;44(5-6):395-400.

PMID:9017158
Abstract

A novel antiviral drug with immunomodulatory activity (Phosprenyl) is presented. The main active ingredient of the preparation is polyprenyl phosphates. This medicine is highly efficient against a number of viruses, including HIV in vitro, and tick-borne encephalitis and rabies viruses in the experimental models in vivo. In veterinary practice Phosprenyl is now regarded as an effective therapeutic means for treatment of canine distemper, hepatitis, enteritis, etc.

摘要

一种具有免疫调节活性的新型抗病毒药物(磷戊酯)已被提出。该制剂的主要活性成分是聚异戊二烯磷酸酯。这种药物对多种病毒具有高效性,包括体外的HIV,以及体内实验模型中的蜱传脑炎病毒和狂犬病病毒。在兽医实践中,磷戊酯现在被视为治疗犬瘟热、肝炎、肠炎等疾病的有效治疗手段。

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