用于肺病小动物模型的新型成像方法（2017年格罗弗会议系列）
Novel imaging approaches for small animal models of lung disease (2017 Grover Conference series).
作者信息
Pinar Isaac P, Jones Heather D
机构信息
1 Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, VIC, Australia.
2 Division of Biological Engineering, Faculty of Engineering, Monash University, Melbourne, VIC, Australia.
出版信息
Pulm Circ. 2018 Apr-Jun;8(2):2045894018762242. doi: 10.1177/2045894018762242. Epub 2018 Feb 26.
Imaging in small animal models of lung disease is challenging, as existing technologies are limited either by resolution or by the terminal nature of the imaging approach. Here, we describe the current state of small animal lung imaging, the technological advances of laboratory-sourced phase contrast X-ray imaging, and the application of this novel technology and its attendant image analysis techniques to the in vivo imaging of the large airways and pulmonary vasculature in murine models of lung health and disease.
在肺部疾病的小动物模型中进行成像具有挑战性，因为现有技术要么受分辨率限制，要么受成像方法的终端性质限制。在此，我们描述了小动物肺部成像的当前状态、实验室来源的相衬X射线成像的技术进展，以及这项新技术及其相关图像分析技术在肺部健康和疾病小鼠模型的大气道和肺血管的体内成像中的应用。
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