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在原发性视网膜脱离修复过程中，眼内注射抗血管内皮生长因子同时治疗近视性脉络膜新生血管和孔源性视网膜脱离。

Concurrent management of myopic choroidal neovascularization and rhegmatogenous retinal detachment with intravitreal antivascular endothelial growth factor during primary retinal detachment repair.

机构信息

Retina Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.

出版信息

Indian J Ophthalmol. 2018 Mar;66(3):472-474. doi: 10.4103/ijo.IJO_856_17.

DOI:10.4103/ijo.IJO_856_17
PMID:29480274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5859618/
Abstract

We report concurrent management of rhegmatogenous retinal detachment and myopic choroidal neovascularization in the left eye of a 24-year-old female who presented with sudden dimness of vision due to retinal detachment and choroidal neovascularization. Intravitreal antivascular endothelial growth factor was injected during primary vitrectomy for retinal detachment. At final follow-up, the retina was attached with scarring of choroidal neovascularization. Ours is the first report of the use of intravitreal antivascular endothelial growth factor during vitrectomy for retinal detachment.

摘要

我们报告了一例 24 岁女性左眼同时患有孔源性视网膜脱离和近视性脉络膜新生血管的病例。该患者因视网膜脱离和脉络膜新生血管而出现视力突然下降，在接受原发性玻璃体切除术治疗视网膜脱离的同时，我们向玻璃体内注射了抗血管内皮生长因子药物。最终随访时，患者视网膜贴附，但脉络膜新生血管出现瘢痕。这是玻璃体切除术中使用玻璃体内抗血管内皮生长因子治疗视网膜脱离的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0bc/5859618/615971196eb0/IJO-66-472-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0bc/5859618/8e3b64e86ca1/IJO-66-472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0bc/5859618/615971196eb0/IJO-66-472-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0bc/5859618/8e3b64e86ca1/IJO-66-472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0bc/5859618/615971196eb0/IJO-66-472-g002.jpg

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本文引用的文献

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2
Intravitreal Ranibizumab for myopic choroidal neovascularization after pars plana vitrectomy and silicone oil tamponade.玻璃体腔注射雷珠单抗治疗玻璃体切割联合硅油填充术后近视性脉络膜新生血管化
Eur J Ophthalmol. 2013 Nov-Dec;23(6):913-6. doi: 10.5301/ejo.5000337. Epub 2013 Jun 23.
3
Intrasilicone bevacizumab injection for iris neovascularization after vitrectomy for proliferative diabetic retinopathy.
玻璃体切除术后增生性糖尿病视网膜病变的虹膜新生血管内注射硅酮贝伐单抗。
Ophthalmic Res. 2013;49(1):20-4. doi: 10.1159/000341734. Epub 2012 Sep 13.
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Ocular pharmacokinetics of bevacizumab in vitrectomized eyes with silicone oil tamponade.硅油填充眼玻璃体切割术后贝伐单抗的眼内药代动力学。
Invest Ophthalmol Vis Sci. 2012 Aug 7;53(9):5221-6. doi: 10.1167/iovs.12-9702.