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急性血压升高:治疗方法。

Acute blood pressure elevation: Therapeutic approach.

机构信息

Department of Clinical and Experimental Sciences University of Brescia, 2a medicina Spedali Civili, Brescia, 25100, Italy.

Department of Clinical and Experimental Sciences University of Brescia, 2a medicina Spedali Civili, Brescia, 25100, Italy.

出版信息

Pharmacol Res. 2018 Apr;130:180-190. doi: 10.1016/j.phrs.2018.02.026. Epub 2018 Feb 23.

Abstract

International guidelines have suggested to avoid the term "hypertensive crisis" for the description of an acute and severe increase in blood pressure (BP) and to consider the definition of 'hypertensive emergencies' or 'hypertensive urgencies'. These two clinical presentations are characterized by the presence of high BP values but imply a different diagnostic and therapeutic approach. Hypertension awareness, treatment and control are slightly increased in the last years mostly in the United States and in some European nations. Nevertheless the prevalence of hypertensive emergencies is still high and remains associated to a higher mortality. International Guidelines have also given some recommendations regarding the target BP during treatment and the use of antihypertensive drugs in hypertensive emergencies, although the adherence to these indications is frequently suboptimal. The present paper is aimed to update the currently available data on the treatment of hypertensive emergencies.

摘要

国际指南建议避免使用“高血压危象”一词来描述血压的急性和严重升高,并考虑使用“高血压急症”或“高血压紧急情况”的定义。这两种临床表现的特点是血压值升高,但需要不同的诊断和治疗方法。近年来,高血压的认识、治疗和控制在美国和一些欧洲国家略有增加。然而,高血压急症的患病率仍然很高,并且仍然与更高的死亡率相关。国际指南还就治疗期间的目标血压和高血压急症中抗高血压药物的使用提出了一些建议,尽管这些建议的依从性往往并不理想。本文旨在更新目前关于高血压急症治疗的可用数据。

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