Papadopoulos Dimitris P, Mourouzis Iordanis, Thomopoulos Costas, Makris Thomas, Papademetriou Vasilios
Hypertension Clinic, Laiko University Hospital, Athens, Greece.
Blood Press. 2010 Dec;19(6):328-36. doi: 10.3109/08037051.2010.488052. Epub 2010 May 27.
Hypertensive crises (76% urgencies, 24% emergencies) represented more than one fourth of all medical urgencies/emergencies. Hypertensive urgencies frequently present with headache (22%), epistaxis (17%), faintness, and psychomotor agitation (10%) and hypertensive emergencies frequently present with chest pain (27%), dyspnea (22%) and neurological deficit (21%). Types of end-organ damage associated with hypertensive emergencies include cerebral infarction (24%), acute pulmonary edema (23%) and hypertensive encephalopathy (16%), as well as cerebral hemorrhage (4.5%). The most important factor that limits morbidity and mortality from these disorders is prompt and carefully considered therapy. Unfortunately, hypertensive emergencies and urgencies are among the most misunderstood and mismanaged of acute medical problems seen today. The primary goal of intervention in a hypertensive crisis is to safely reduce BP. Immediate reduction in BP is required only in patients with acute end-organ damage (i.e. hypertensive emergency). This requires treatment with a titratable short-acting intravenous (IV) antihypertensive agent, while severe hypertension with no acute end-organ damage is usually treated with oral antihypertensive agents. Patients with hypertensive emergencies are best treated in an intensive care unit (ICU) with titratable IV hypotensive agents. The aim of this review is to summarize the details regarding the definition-impact, causes, clinical condition and management of hypertensive crises.
高血压急症(76%为紧急情况,24%为急症)占所有医疗紧急情况的四分之一以上。高血压紧急情况常表现为头痛(22%)、鼻出血(17%)、头晕和精神运动性激越(10%),而高血压急症常表现为胸痛(27%)、呼吸困难(22%)和神经功能缺损(21%)。与高血压急症相关的靶器官损害类型包括脑梗死(24%)、急性肺水肿(23%)和高血压脑病(16%),以及脑出血(4.5%)。限制这些疾病发病率和死亡率的最重要因素是及时且经过仔细考虑的治疗。不幸的是,高血压急症和紧急情况是当今所见急性医疗问题中最易被误解和处理不当的情况之一。高血压急症干预的主要目标是安全降低血压。仅在有急性靶器官损害的患者(即高血压急症)中需要立即降低血压。这需要使用可滴定的短效静脉内(IV)抗高血压药物进行治疗,而无急性靶器官损害的重度高血压通常用口服抗高血压药物治疗。高血压急症患者最好在重症监护病房(ICU)用可滴定的IV降压药物进行治疗。本综述的目的是总结有关高血压急症的定义 - 影响、病因、临床状况和管理的详细信息。