Liu Ren-Feng, Kuo Tseng-Tong, Chao Yen-Yu, Huang Yu-Huei
a Department of Dermatology , Chang Gung Memorial Hospital , Taipei and Linko , Taiwan.
b Department of Pathology , Chang Gung Memorial Hospital , Linko , Taiwan.
J Cosmet Laser Ther. 2018 Nov-Dec;20(7-8):462-464. doi: 10.1080/14764172.2018.1427867. Epub 2018 Feb 26.
Radiesse is a soft tissue filler which has been widely used for cosmetic enhancement. The safety of Radiesse has been thoroughly investigated via numerous studies. A late-onset complication of Radiesse injection consists of foreign body granulomas, with only three case reports in over 10 years of clinical use. Herein, we describe the case of a patient who experienced alopecia with foreign body granulomas at the injection region one month after receiving a Radiesse injection. To our knowledge, this is the first report in the English literature of alopecia as an adverse event associated with Radiesse injection. The present case reminded physicians to evaluate more cautiously the necessity of injecting filler into hair-bearing area for lifting purpose. This procedure may cause foreign body granulomatous reaction, which may result in hair loss at the injection region.
瑞蓝（Radiesse）是一种软组织填充剂，已被广泛用于美容增强。通过大量研究对瑞蓝的安全性进行了全面调查。瑞蓝注射的一种迟发性并发症是异物肉芽肿，在超过10年的临床使用中仅有3例病例报告。在此，我们描述了一名患者在接受瑞蓝注射后1个月，注射部位出现伴有异物肉芽肿的脱发情况。据我们所知，这是英文文献中关于脱发作为与瑞蓝注射相关的不良事件的首例报告。本病例提醒医生在为提升目的而向有毛发区域注射填充剂时要更谨慎地评估必要性。此操作可能会引起异物肉芽肿反应，这可能导致注射部位脱发。
