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[斯维尔德洛夫斯克地区儿童群体针对腮腺炎病毒的免疫结构及腮腺炎病因引起的浆液性脑膜炎发病率]

[Immune structure of the pediatric population in relation to the mumps virus and the morbidity of serous meningitis of mumps etiology in Sverdlovsk].

作者信息

Venediktova N Ia, Kolpakova V E, Kozlova S N, Zakirova S F, Lavrinova R V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1986 Nov(11):31-4.

PMID:2948352
Abstract

The work presents the results of the longterm study of regularities in the formation of herd immunity to mumps virus in children in Sverdlovsk with due regard to vaccination carried out in this city and morbidity level in serous meningitis of mumps etiology. The inverse correlation between the number of seropositive persons in the total child population and the level of morbidity in the nervous form of mumps has been established. No differences in the size of the immune stratum and the intensity of immunity to mumps virus among boys and girls have been revealed. Vaccination against mumps, carried out at the period of a natural drop in mumps morbidity, has produced no essential effect on the level of herd immunity, though it has led to a considerable decrease in the incidence of serous meningitis of mumps etiology.

摘要

该研究呈现了斯维尔德洛夫斯克儿童群体中腮腺炎病毒群体免疫形成规律的长期研究结果,其中考虑了该市开展的疫苗接种情况以及腮腺炎病因性浆液性脑膜炎的发病水平。已确定儿童总人口中血清阳性人数与腮腺炎神经型发病水平之间呈负相关。未发现男孩和女孩在对腮腺炎病毒的免疫层大小和免疫强度方面存在差异。在腮腺炎发病率自然下降期间进行的腮腺炎疫苗接种,对群体免疫水平没有产生实质性影响,尽管它导致腮腺炎病因性浆液性脑膜炎的发病率大幅下降。

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