1 Department of Otolaryngology-Head and Neck Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Otolaryngol Head Neck Surg. 2018 Jun;158(6):1113-1118. doi: 10.1177/0194599818760513. Epub 2018 Feb 27.
Objectives To use decision analysis modeling to compare utility and cost outcomes of intracapsular tonsillectomy (ICT) and extracapsular tonsillectomy (ECT). To use sensitivity analysis to determine the most important factors influencing outcomes favoring one surgical method versus another. Study Design Decision analysis model. Setting Hypothetical cohort. Subjects and Methods A decision analysis model was created with computer software comparing the results of ICT and ECT. The model featured complications with completion tonsillectomy, such as postsurgical bleed, dehydration, and tonsillar regrowth. Outcomes were quantified with a utility scale ranging from 0.95 (1 surgical procedure without complications) to 0.55 (ICT, regrowth requiring completion ECT, post-ECT bleeding). Costs measured out-of-pocket costs for an insured patient and factored in different recovery times for ECT versus ICT. Results Based on baseline parameters, ECT had higher cumulative utility than ICT. Utility model results were highly dependent on the value of having a single uncomplicated surgery, as well as on the tonsillar regrowth rate. Utility was equal at a regrowth rate of 1.64%; rates above this value favored ECT. The base cost model showed that ICT ($4177.92) was less expensive than ECT ($4546.91), although ICT with regrowth had the highest outcome cost ($8393.91). ECT and ICT costs were equal at a tonsil regrowth rate of 17.8% and at a recovery period of 7.4 days. Conclusion Utility decision modeling based on best estimates for baseline parameters suggests that ECT may be slightly superior to ICT, but cost analysis suggests the opposite. However, the comparative results are highly dependent on subtle changes in the tonsil regrowth rate and the potential difference in recovery time.
使用决策分析模型比较囊内扁桃体切除术(ICT)和囊外扁桃体切除术(ECT)的效用和成本结果。使用敏感性分析确定影响手术方法选择的最重要因素。
决策分析模型。
假设队列。
使用计算机软件创建了一个决策分析模型,比较 ICT 和 ECT 的结果。该模型具有完成扁桃体切除术的并发症,如术后出血、脱水和扁桃体再生。结果用效用量表来量化,范围从 0.95(无并发症的 1 次手术)到 0.55(ICT,再生需要完成 ECT,ECT 后出血)。成本衡量了有保险的患者的自付费用,并考虑了 ECT 与 ICT 不同的恢复时间。
基于基线参数,ECT 的累积效用高于 ICT。效用模型的结果高度依赖于单次无并发症手术的价值,以及扁桃体再生的速度。在再生率为 1.64%时,效用相等;高于这个值的再生率有利于 ECT。基本成本模型显示,ICT(4177.92 美元)比 ECT(4546.91 美元)便宜,尽管 ICT 加上再生的总费用最高(8393.91 美元)。ECT 和 ICT 的成本在扁桃体再生率为 17.8%和恢复时间为 7.4 天时相等。
基于基线参数的最佳估计值的效用决策模型表明,ECT 可能略优于 ICT,但成本分析表明情况相反。然而,比较结果高度依赖于扁桃体再生率的微小变化和潜在的恢复时间差异。