Lui S-A, Oh H B, Wang S, Chan C W
Division of Breast Surgery, Department of Surgery, National University Health System , Singapore.
Department of Pathology, National University Hospital, National University Health System , Singapore.
Ann R Coll Surg Engl. 2018 Apr;100(4):e97-e102. doi: 10.1308/rcsann.2018.0024. Epub 2018 Feb 27.
Ductal carcinoma in situ arising within a benign phyllodes tumour is a rare neoplasm of the breast. We present a case of a 19-year-old woman who had a right breast lump for six months with the above diagnosis together with a mini-review of the literature. Ultrasound revealed a 5-cm breast lump and core biopsy revealed ductal carcinoma in situ. She underwent wide local excision of the breast lump with clear margins. Final histology confirmed ductal carcinoma in situ within a fibroepithelial lesion consistent with a benign phyllodes tumour. To our knowledge, this is the youngest case of ductal carcinoma in situ arising in a phyllodes tumour to have been reported so far.
起源于良性叶状肿瘤内的导管原位癌是一种罕见的乳腺肿瘤。我们报告一例19岁女性，她右乳肿块6个月，诊断为此病，并对相关文献进行简要回顾。超声显示一个5厘米的乳腺肿块，粗针活检显示为导管原位癌。她接受了乳腺肿块的局部广泛切除，切缘清晰。最终组织学检查证实，在符合良性叶状肿瘤的纤维上皮病变内存在导管原位癌。据我们所知，这是迄今为止报道的起源于叶状肿瘤的最年轻的导管原位癌病例。
