University of Michigan, Ann Arbor, Michigan.
University of Michigan, Ann Arbor, Michigan.
Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):1057-1066. doi: 10.1016/j.ijrobp.2017.12.013. Epub 2017 Dec 15.
A substantial barrier to the single- and multi-institutional aggregation of data to supporting clinical trials, practice quality improvement efforts, and development of big data analytics resource systems is the lack of standardized nomenclatures for expressing dosimetric data. To address this issue, the American Association of Physicists in Medicine (AAPM) Task Group 263 was charged with providing nomenclature guidelines and values in radiation oncology for use in clinical trials, data-pooling initiatives, population-based studies, and routine clinical care by standardizing: (1) structure names across image processing and treatment planning system platforms; (2) nomenclature for dosimetric data (eg, dose-volume histogram [DVH]-based metrics); (3) templates for clinical trial groups and users of an initial subset of software platforms to facilitate adoption of the standards; (4) formalism for nomenclature schema, which can accommodate the addition of other structures defined in the future. A multisociety, multidisciplinary, multinational group of 57 members representing stake holders ranging from large academic centers to community clinics and vendors was assembled, including physicists, physicians, dosimetrists, and vendors. The stakeholder groups represented in the membership included the AAPM, American Society for Radiation Oncology (ASTRO), NRG Oncology, European Society for Radiation Oncology (ESTRO), Radiation Therapy Oncology Group (RTOG), Children's Oncology Group (COG), Integrating Healthcare Enterprise in Radiation Oncology (IHE-RO), and Digital Imaging and Communications in Medicine working group (DICOM WG); A nomenclature system for target and organ at risk volumes and DVH nomenclature was developed and piloted to demonstrate viability across a range of clinics and within the framework of clinical trials. The final report was approved by AAPM in October 2017. The approval process included review by 8 AAPM committees, with additional review by ASTRO, European Society for Radiation Oncology (ESTRO), and American Association of Medical Dosimetrists (AAMD). This Executive Summary of the report highlights the key recommendations for clinical practice, research, and trials.
将数据用于支持临床试验、实践质量改进工作以及开发大数据分析资源系统的一个主要障碍是缺乏用于表达剂量学数据的标准化命名法。为了解决这个问题,美国医学物理学家协会(AAPM)第 263 任务组负责为放射肿瘤学提供命名指南和值,用于临床试验、数据汇总计划、基于人群的研究和常规临床护理,方法是标准化:(1)跨图像处理和治疗计划系统平台的结构名称;(2)剂量学数据的命名(例如,基于剂量体积直方图[DVH]的指标);(3)临床试验组的模板和初始软件平台子集的用户,以促进标准的采用;(4)命名法模式的形式主义,可以容纳未来定义的其他结构。一个由 57 名成员组成的多学会、多学科、多国小组代表了从大型学术中心到社区诊所和供应商的利益相关者,包括物理学家、医生、剂量师和供应商。成员代表的利益相关者群体包括 AAPM、美国放射肿瘤学会(ASTRO)、NRG 肿瘤学、欧洲放射肿瘤学会(ESTRO)、放射治疗肿瘤学组(RTOG)、儿童肿瘤学组(COG)、放射肿瘤学中的集成医疗企业(IHE-RO)和数字成像和通信工作组(DICOM WG);制定了靶区和危及器官体积和 DVH 命名法的命名系统,并在一系列诊所和临床试验框架内进行了试点,以证明其可行性。最终报告于 2017 年 10 月获得 AAPM 批准。该批准过程包括 AAPM 8 个委员会的审查,ASTRO、欧洲放射肿瘤学会(ESTRO)和美国医学剂量师协会(AAMD)的额外审查。该报告的执行摘要重点介绍了临床实践、研究和试验的关键建议。