Department of Radiation Oncology, University of California Davis Cancer Center, Sacramento, California; Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, Arizona.
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia.
Pract Radiat Oncol. 2021 Jul-Aug;11(4):282-298. doi: 10.1016/j.prro.2021.02.007. Epub 2021 Mar 2.
The registration of multiple imaging studies to radiation therapy computed tomography simulation, including magnetic resonance imaging, positron emission tomography-computed tomography, etc. is a widely used strategy in radiation oncology treatment planning, and these registrations have valuable roles in image guidance, dose composition/accumulation, and treatment delivery adaptation. The NRG Oncology Medical Physics subcommittee formed a working group to investigate feasible workflows for a self-study credentialing process of image registration commissioning.
The American Association of Physicists in Medicine (AAPM) Task Group 132 (TG132) report on the use of image registration and fusion algorithms in radiation therapy provides basic guidelines for quality assurance and quality control of the image registration algorithms and the overall clinical process. The report recommends a series of tests and the corresponding metrics that should be evaluated and reported during commissioning and routine quality assurance, as well as a set of recommendations for vendors. The NRG Oncology medical physics subcommittee working group found incompatibility of some digital phantoms with commercial systems. Thus, there is still a need to provide further recommendations in terms of compatible digital phantoms, clinical feasible workflow, and achievable thresholds, especially for future clinical trials involving deformable image registration algorithms. Nine institutions participated and evaluated 4 commonly used commercial imaging registration software and various versions in the field of radiation oncology.
The NRG Oncology Working Group on image registration commissioning herein provides recommendations on the use of digital phantom/data sets and analytical software access for institutions and clinics to perform their own self-study evaluation of commercial imaging systems that might be employed for coregistration in radiation therapy treatment planning and image guidance procedures. Evaluation metrics and their corresponding values were given as guidelines to establish practical tolerances. Vendor compliance for image registration commissioning was evaluated, and recommendations were given for future development.
将多个成像研究（包括磁共振成像、正电子发射断层扫描计算机断层扫描等）注册到放射治疗计算机断层扫描模拟中，是放射肿瘤治疗计划中广泛使用的策略，这些注册在图像引导、剂量组成/积累和治疗交付适应方面具有重要作用。NRG 肿瘤学医学物理分会成立了一个工作组，研究图像配准认证的自学工作流程的可行性。
美国医学物理学家协会（AAPM）第 132 工作组（TG132）报告了在放射治疗中使用图像配准和融合算法的基本指南，为图像配准算法和整体临床过程的质量保证和质量控制提供了基本指南。该报告建议在认证和常规质量保证期间应评估和报告一系列测试以及相应的指标，并为供应商提供了一系列建议。NRG 肿瘤学医学物理分会工作组发现一些数字体模与商业系统不兼容。因此，在兼容的数字体模、临床可行的工作流程和可实现的阈值方面仍需要提供进一步的建议，特别是对于涉及可变形图像配准算法的未来临床试验。九个机构参与并评估了 4 种常用的商业成像注册软件及其在放射肿瘤学领域的各种版本。
NRG 肿瘤学成像配准认证工作组在此提供了有关数字体模/数据集和分析软件访问的使用建议，以供机构和临床使用，以对其可能用于放射治疗计划和图像引导程序中的核心配准的商业成像系统进行自己的自学评估。评估指标及其相应值作为建立实用公差的指南给出。评估了图像配准认证的供应商合规性，并为未来的发展提出了建议。
