Uzel Mehmet Murat, Ozates Serdar, Koc Mustafa, Taslipinar Uzel Ayse Guzin, Yılmazbaş Pelin
a Elmadag State Hospital, Ophthalmology Department , Ankara , Turkey.
b Ulucanlar Eye Research and Training Hospital , Ophthalmology Department , Ankara , Turkey.
Semin Ophthalmol. 2018;33(6):766-771. doi: 10.1080/08820538.2018.1443146. Epub 2018 Feb 27.
To assess the effect of posterior capsular opacification (PCO) and Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on tilt and decentration of intraocular lens (IOL) at vertical and horizontal meridians.
The study included 64 eyes of 64 patients. IOL decentration and tilt were measured using a Scheimpflug camera before and 1 month after Nd:YAG capsulotomy. Corrected distance visual acuity (CDVA) and manifest refraction were also determined. Between-group differences of IOL position change and the effect of Nd:YAG laser capsulotomy were analyzed.
In the PCO group, before capsulotomy, CDVA was significantly lower than that after capsulotomy and of the control group values (p = 0.001 for both). No significant difference was observed in CDVA between the control group and the PCO group after capsulotomy (p = 0.854). Before capsulotomy, the angle of tilt and decentration at both meridians was significantly higher than that in the control group (tilt: p < 0.001; for both decentrations: p = 0.001, p = 0.003, respectively). A significant decrease was observed in the angle of tilt at both meridians (horizontal p = 0.001, vertical p = 0.001) from before to after capsulotomy in the PCO group. Although decentration was increased after capsulotomy, no significant position change was observed (horizontal p = 0.350, vertical p = 0.107). The angle of tilt and decentration at both meridians was significantly higher in the PCO group after capsulotomy compared to the control group (p < 0.001 for all).
PCO is associated with not only axial displacement, but also tilt and decentration of IOL at the vertical and horizontal meridians. Laser capsulotomy decreased IOL tilt but had no effect on decentration. However, these changes did not significantly change the visual acuity between the control group and the PCO group after capsulotomy.
评估后囊膜混浊(PCO)及钕掺杂钇铝石榴石(Nd:YAG)激光晶状体囊切开术对人工晶状体(IOL)在垂直和水平子午线上倾斜及偏心的影响。
该研究纳入了64例患者的64只眼。在Nd:YAG晶状体囊切开术前及术后1个月,使用Scheimpflug相机测量IOL的偏心和倾斜情况。同时还测定了矫正远视力(CDVA)和显验光。分析了IOL位置变化的组间差异以及Nd:YAG激光晶状体囊切开术的效果。
在PCO组中,晶状体囊切开术前的CDVA显著低于晶状体囊切开术后及对照组的值(两者p均 = 0.001)。晶状体囊切开术后,对照组与PCO组的CDVA无显著差异(p = 0.854)。晶状体囊切开术前,两个子午线上的倾斜角度和偏心度均显著高于对照组(倾斜:p < 0.001;两个偏心度分别为:p = 0.001,p = 0.003)。PCO组在晶状体囊切开术前至术后,两个子午线上的倾斜角度均显著降低(水平p = 0.001,垂直p = 0.001)。虽然晶状体囊切开术后偏心度增加,但未观察到显著的位置变化(水平p = 0.350,垂直p = 0.107)。晶状体囊切开术后,PCO组两个子午线上的倾斜角度和偏心度均显著高于对照组(所有p < 0.001)。
PCO不仅与轴向移位有关,还与IOL在垂直和水平子午线上的倾斜及偏心有关。激光晶状体囊切开术可降低IOL倾斜,但对偏心无影响。然而,这些变化在晶状体囊切开术后并未显著改变对照组与PCO组之间的视力。