Eye Clinic JL FBMI CVUT Prague, Czech Republic.
Faculty of Biomedical Engineering, CVUT in Prague, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022 May;166(2):211-216. doi: 10.5507/bp.2021.014. Epub 2021 Mar 12.
The aim of this study was to evaluate the changes in IOL position (axial shift, tilt and decentration) in the capsular bag after Nd:YAG laser capsulotomy and to create a user-friendly software that is optimized for the output of available imaging technology, then verify the relationship between the biometric parameters of the eye and the extent of changes in the IOL position.
The study included 35 artephakic eyes that underwent laser capsulotomy. Before and at least one hour after capsulotomy, all patients underwent the following assessments: optical biometry (Lenstar LS900), OCT with anterior segment module (Optovue Avanti) and IOL photography in infrared mode using reference unit (Verion). The original software solution was designed for the graphical evaluation of the differences between centering, axial displacement and tilt of IOL. Changes in IOL position were evaluated as simple differences before and after the laser procedure and as differences in absolute values (abs).
The following results show the average differences in IOL position: ACD=0.02±0.23 mm (abs=0.11±0.20 mm), IOL decentration in x-axis = -0.001±0.091 mm (abs=0.065±0.063 mm), IOL decentration in y-axis =0.012±0.119 mm (abs=0.048±0.53 mm), tilt in horizontal plane TILT-H=0.11±0.83° (abs=0.51±0.66°) and tilt in vertical plane TILT-V = -0.14±0.49° (abs=0.26±0.44°). All changes were insignificant (P>>0.05). In total, 74.29% of IOLs showed a hypermetropic shift. A moderate positive correlation was found between the absolute differences in horizontal tilt and keratometry (r=0.45). Relationship with other changes and parameters were weak.
In conclusion, the use of the original software solution developed by the authors showed that changes in IOL centering, axial displacement and tilt occur after Nd:YAG capsulotomy, but average differences were insignificant. In almost 3/4 cases, there was a hypermetropic axial displacement of the IOL.
本研究旨在评估 Nd:YAG 激光后囊切开术后人工晶状体（IOL）在囊袋内位置（轴向移位、倾斜和偏心）的变化，并创建一个用户友好的软件，该软件针对现有成像技术的输出进行了优化，然后验证眼生物测量参数与 IOL 位置变化程度之间的关系。
这项研究包括 35 例人工晶状体眼，这些眼均接受了激光后囊切开术。在激光后囊切开术之前和至少 1 小时后，所有患者均接受了以下评估：光学生物测量（Lenstar LS900）、前节模块的光学相干断层扫描（Optovue Avanti）和使用参考单元（Verion）的红外模式下的 IOL 摄影。原始软件解决方案是专为图形评估 IOL 定心、轴向位移和倾斜之间的差异而设计的。IOL 位置的变化被评估为激光手术后的简单差异和绝对值差异（abs）。
以下是 IOL 位置平均差异的结果：ACD=0.02±0.23mm（abs=0.11±0.20mm），IOL 在 x 轴上的偏心= -0.001±0.091mm（abs=0.065±0.063mm），IOL 在 y 轴上的偏心=0.012±0.119mm（abs=0.048±0.53mm），水平平面倾斜 TILT-H=0.11±0.83°（abs=0.51±0.66°），垂直平面倾斜 TILT-V=-0.14±0.49°（abs=0.26±0.44°）。所有变化均无统计学意义（P>>0.05）。总共，74.29%的 IOL 显示远视性移位。水平倾斜的绝对值与角膜曲率计之间存在中度正相关（r=0.45）。与其他变化和参数的关系较弱。
总之，作者开发的原始软件解决方案的使用表明，Nd:YAG 后囊切开术后 IOL 定心、轴向位移和倾斜发生变化，但平均差异无统计学意义。在近 3/4 的情况下，IOL 存在轴向远视性位移。
