Akinwande K S, Morenikeji O A, Arinola O G
Department of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan.
Niger J Physiol Sci. 2017 Dec 30;32(2):195-200.
Adequate nutrition is essential for normal growth of children but helminth infection is proposed to cause nutritional deficiencies. This study was carried out to assess the nutritional status of helminth infected school aged children in semi-urban communities of South-West Nigeria. Two hundred children from primary schools in Akinyele Local Government of Oyo State, Nigeria participated in the study. Anthropometric measurements were analyzed using the WHO AnthroPlus software. Kato Katz method was used to detect ova of helminths in the stool while serum levels of iron, zinc, selenium, ferritin, transferrin, vitamin A, vitamin C and haptoglobin were measured using High Performance Liquid Chromatography and Atomic Absorption Spectophotometry as appropriate. 60 (30%) of the children had intestinal helminth infection with Ascaris lumbricoides (23.0%) as most prevalent, followed by hookworm (2.5%) and Trichuris trichuria (0.5%). Stunting was more prevalent than thinness or underweight among the study population especially the female children. There were significantly reduced serum levels of zinc and vitamin A and significantly increased serum levels of transferrin and selenium in helminth-infected children compared with helminth-uninfected children. This study established the need for regular deworming of school age children and supplementing diets of school children in rural communities with vitamin A and zinc.
充足的营养对儿童正常生长至关重要,但有观点认为蠕虫感染会导致营养缺乏。本研究旨在评估尼日利亚西南部半城市社区感染蠕虫的学龄儿童的营养状况。来自尼日利亚奥约州阿金耶勒地方政府小学的200名儿童参与了该研究。使用世界卫生组织AnthroPlus软件分析人体测量数据。采用加藤厚涂片法检测粪便中的蠕虫卵,同时根据情况使用高效液相色谱法和原子吸收分光光度法测量血清中铁、锌、硒、铁蛋白、转铁蛋白、维生素A、维生素C和触珠蛋白的水平。60名(30%)儿童患有肠道蠕虫感染,其中蛔虫感染最为普遍(23.0%),其次是钩虫感染(2.5%)和鞭虫感染(0.5%)。在研究人群中,尤其是女童,发育迟缓比消瘦或体重不足更为普遍。与未感染蠕虫的儿童相比,感染蠕虫的儿童血清锌和维生素A水平显著降低,血清转铁蛋白和硒水平显著升高。本研究确定了对学龄儿童定期驱虫以及为农村社区学童补充维生素A和锌的必要性。