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The hydroxamate of valproic acid, a compound produced by oximation of urine from patients under valproic therapy.

作者信息

Libert R, Van Hoof F, Schanck A, Hoffmann E

出版信息

Biomed Environ Mass Spectrom. 1986 Nov;13(11):599-603. doi: 10.1002/bms.1200131104.

Abstract

A previously unreported substance, detected by gas chromatography after oximation of urine from patients receiving valproic acid, was isolated and analysed by mass spectrometry and nuclear magnetic resonance spectroscopy. It was identified as the hydroxamate of valproic acid.

摘要

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The hydroxamate of valproic acid, a compound produced by oximation of urine from patients under valproic therapy.
Biomed Environ Mass Spectrom. 1986 Nov;13(11):599-603. doi: 10.1002/bms.1200131104.
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Five doubly unsaturated metabolites of valproic acid in urine and plasma of patients on valproic acid therapy.
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