Identification of urinary metabolites of sodium dipropylacetate in man; potential sources of interference in organic acid screening procedures.
作者信息
Gompertz D, Tippett P, Bartlett K, Baillie T
出版信息
Clin Chim Acta. 1977 Jan 17;74(2):153-60. doi: 10.1016/0009-8981(77)90216-9.
PMID:318946
Abstract
Organic acid screening of urine samples from two children with neurological disease demonstrated the presence of two unknown metabolites. The children were receiving an antiepileptic drug, sodium dipropylacetate. The major abnormal compound has been shown by gas chromatography-mass spectrometry to be 3-oxodipropylacetic acid, a previously unidentified metabolite of dipropylacetate in man, while the minor metabolite was indentified as 2-(n-propyl)-glutaric acid.
摘要
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