Cross-resistance of menogaril and mitoxantrone in a subline of P388 leukemia resistant to doxorubicin.
作者信息
Chandrasekaran B, Dimling J, Capizzi R L
出版信息
Cancer Treat Rep. 1987 Feb;71(2):195-6.
PMID:2948640
Abstract
Mice bearing the P388/S or P388/ADR (doxorubicin-resistant) leukemia were treated with menogaril or mitoxantrone. Both drugs were highly effective against P388/S but were ineffective against the doxorubicin-resistant subline, indicating cross-resistance. These observations may be of use in the design of clinical trials with these drugs.
摘要
Zotero 插件