一种在子宫肌瘤栓塞术中降低辐射剂量的新型成像技术。

A new imaging technology to reduce the radiation dose during uterine fibroid embolization.

作者信息

Thomaere Eveline, Dehairs Michiel, Laenen Annouschka, Mehrsima Abdoli, Timmerman Dirk, Cornelissen Sandra, Op de Beeck Katya, Bosmans Hilde, Maleux Geert

机构信息

1 Department of Radiology, University Hospitals Leuven, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.

2 Department of Radiology, Section of Medical Physics, University Hospitals Leuven, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.

出版信息

Acta Radiol. 2018 Dec;59(12):1446-1450. doi: 10.1177/0284185118760064. Epub 2018 Feb 27.

DOI:10.1177/0284185118760064

PMID:29486598

Abstract

BACKGROUND

Uterine fibroid embolization (UFE) is a minimally invasive imaging-guided treatment using radiation exposure.

PURPOSE

To compare the patients' radiation exposure during UFE before and after introduction of a new X-ray imaging platform.

MATERIAL AND METHODS

Forty-one patients were enrolled in a prospective, comparative two-arm project before and after introduction of a new X-ray imaging platform with reduced dose settings, i.e. novel real-time image processing techniques (AlluraClarity). Demographic, pre-interventional imaging, and procedural data, including dose area product (DAP) and estimated organ dose on the ovaries and uterus, were recorded and angiographic quality of overall procedure was assessed.

RESULTS

There were no significant differences in demographic characteristics and preoperative fibroid and uterine volumes in the two groups. The new imaging platform led to a significant reduction in mean total DAP (102 vs. 438 Gy.cm; P < 0.001), mean fluoroscopy DAP (32 vs. 138 Gy.cm; P < 0.001), mean acquisition DAP (70 vs. 300 Gy.cm; P < 0.001), and acquisition DAP estimated organ dose in ovaries (42 vs. 118 mGy; P < 0.001) and uterus (40 vs. 118 mGy, P < 0.001), without impairment of the procedure and angiographic image quality.

CONCLUSION

A substantial 77% reduction of DAP values and 64% and 66% reduction in organ dose on ovaries and uterus, respectively, was demonstrated with the new imaging platform, while maintaining optimal imaging quality and efficacy.

摘要

背景

子宫肌瘤栓塞术（UFE）是一种使用辐射暴露的微创影像引导治疗方法。

目的

比较新型X射线成像平台引入前后子宫肌瘤栓塞术期间患者的辐射暴露情况。

材料与方法

在引入具有降低剂量设置的新型X射线成像平台（即新型实时图像处理技术（AlluraClarity））前后，41例患者参与了一项前瞻性、双臂对比项目。记录人口统计学、介入前影像学和手术数据，包括剂量面积乘积（DAP）以及卵巢和子宫的估计器官剂量，并评估整个手术的血管造影质量。

结果

两组在人口统计学特征、术前肌瘤和子宫体积方面无显著差异。新的成像平台使平均总DAP显著降低（102 vs. 438 Gy.cm；P < 0.001），平均透视DAP显著降低（32 vs. 138 Gy.cm；P < 0.001），平均采集DAP显著降低（70 vs. 300 Gy.cm；P < 0.001），卵巢采集DAP估计器官剂量显著降低（42 vs. 118 mGy；P < 0.001），子宫采集DAP估计器官剂量显著降低（40 vs. 118 mGy，P < 0.001），且不影响手术和血管造影图像质量。