Waldhausen John H T, Richards Morgan
Department of Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.
Clin Colon Rectal Surg. 2018 Mar;31(2):121-126. doi: 10.1055/s-0037-1609027. Epub 2018 Feb 25.
Cystic fibrosis is one of the most common inheritable traits in Caucasians. Meconium ileus and its potential complications are the most likely reasons that these patients will need surgical care. Surgical intervention is usually needed in the neonatal period but may also be required later in life. This article discusses the various ways cystic fibrosis can affect the gastrointestinal tract. Both the operative and nonoperative management of complicated and uncomplicated meconium ileus are discussed in the neonatal period as well as long-term issues, such as distal intestinal obstructive syndrome, fibrosing colonopathy, and rectal prolapse, all of which may be seen in older children and adults.
囊性纤维化是白种人中最常见的可遗传性状之一。胎粪性肠梗阻及其潜在并发症是这些患者最可能需要手术治疗的原因。手术干预通常在新生儿期进行,但也可能在生命后期需要。本文讨论了囊性纤维化影响胃肠道的各种方式。新生儿期讨论了复杂和不复杂胎粪性肠梗阻的手术和非手术管理以及长期问题,如远端肠道梗阻综合征、纤维性结肠病和直肠脱垂,所有这些在大龄儿童和成人中都可能出现。