Eckhert C D, Hafeman D B
Curr Eye Res. 1986 Dec;5(12):911-7. doi: 10.3109/02713688608995171.
In the retina, the membranous outer segments shed from the photoreceptors are phagocytized by the adjacent retinal pigment epithelial cells. These cells are some of the most active phagocytic cells in the body and like photoreceptors must survive the lifetime of the organism. The initiation of engulfment by the pigment epithelial cells occurs by an unidentified mechanism. The ingestion of particles by many, but not all phagocytic cells, is mediated by Fc and C3 receptors located on the external plasma membrane. The present experiment reports our unsuccessful attempt to demonstrate either the Fc or C3b receptor on the plasma membrane of RCS rat pigment epithelial cells.
在视网膜中，光感受器脱落的膜性外节被相邻的视网膜色素上皮细胞吞噬。这些细胞是体内一些最活跃的吞噬细胞，与光感受器一样，必须存活于生物体的整个生命周期。色素上皮细胞吞噬作用的起始机制尚不清楚。许多（但并非所有）吞噬细胞摄取颗粒是由位于细胞外质膜上的Fc和C3受体介导的。本实验报告了我们未能在RCS大鼠色素上皮细胞质膜上证明存在Fc或C3b受体的尝试。
