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经口内镜下肌切开术期间的膀胱压力监测及与一氧化碳气体相关的不良事件

Bladder pressure monitoring and CO gas-related adverse events during per-oral endoscopic myotomy.

作者信息

Yamashita-Ichimura Mari, Toyama Emiko, Sasoh Makoto, Shiwaku Hironari, Yamashita Kanefumi, Yamashita Yuichi, Yamaura Ken

机构信息

Department of Anesthesiology, Fukuoka University Hospital, 7-45-1 Nanakuma, Fukuoka, Japan.

Department of Anesthesiology, Showa University Hospital, 1-5-8 Hatanodai, Shinagawa, Tokyo, Japan.

出版信息

J Clin Monit Comput. 2018 Dec;32(6):1111-1116. doi: 10.1007/s10877-018-0122-7. Epub 2018 Feb 27.

Abstract

Per-oral endoscopic myotomy (POEM) is a minimally invasive treatment for esophageal achalasia. However, POEM has the potential risk of inducing carbon dioxide (CO) gas-related adverse events, such as pneumoperitoneum, pneumomediastinum, and pneumothorax. The aim of this study was to evaluate the usability of bladder pressure monitoring as an index of CO gas-related pneumoperitoneum. The monitoring of bladder pressure and lung compliance and the incidence of iatrogenic pneumoperitoneum were retrospectively studied in 20 patients who underwent POEM between June 2013 and March 2015. The bladder pressure was measured using a Foley catheter. Abdominal distention was found in nine patients. The bladder pressure was significantly higher in the nine patients with the distention findings compared with patients without distention [7 (6-9) mmHg vs. 1 (0-2) mmHg; P < 0.05]; however, the decrease in dynamic lung compliance was not significantly different compared with patients without distention [- 7 (- 9.3 to - 5.1) vs. - 5 (- 10.2 to - 1.3) ml/cmHO; P = 0.62]. Based on postoperative changes on CT scans; the following were the observations: pneumomediastinum (55%), minor pneumothorax (5%), pleural effusion (45%), atelectasis (15%), pneumoperitoneum (85%), and subcutaneous emphysema (15%). No significant clinical status was found among the patients postoperatively. Bladder pressure monitoring might be useful for detecting pneumoperitoneum during POEM.

摘要

经口内镜下肌切开术(POEM)是治疗食管贲门失弛缓症的一种微创治疗方法。然而,POEM有诱发二氧化碳(CO)气体相关不良事件的潜在风险,如气腹、纵隔气肿和气胸。本研究的目的是评估膀胱压力监测作为CO气体相关气腹指标的可用性。对2013年6月至2015年3月期间接受POEM治疗的20例患者进行回顾性研究,监测膀胱压力、肺顺应性及医源性气腹的发生率。使用Foley导管测量膀胱压力。9例患者出现腹部膨隆。与未出现腹部膨隆的患者相比,出现膨隆的9例患者的膀胱压力显著更高[7(6 - 9)mmHg对1(0 - 2)mmHg;P < 0.05];然而,与未出现腹部膨隆的患者相比,动态肺顺应性的降低无显著差异[-7(-9.3至-5.1)对-5(-10.2至-1.3)ml/cmH₂O;P = 0.62]。根据术后CT扫描的变化,观察结果如下:纵隔气肿(55%)、少量气胸(5%)、胸腔积液(45%)、肺不张(15%)、气腹(85%)和皮下气肿(15%)。术后患者未发现明显临床症状。膀胱压力监测可能有助于在POEM手术期间检测气腹。

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