Lapchenko A S, Kucherov A G, Order R Ya, Lapchenko A A
Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Moscow, Russia, 117997; L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.
Vestn Otorinolaringol. 2018;83(1):62-64. doi: 10.17116/otorino201883162-64.
The objective of the present study was the enhancement of the effectiveness of the treatment of the consequences of the gunshot wounds and mine-blast injuries inflicted to the face, head, and neck encountered in the otolaryngological practice as well as the prevention of the formation of the large demarcation areas in the injured tissues and the preparation of these tissues for the further restorative treatment. Anti-microbial and anti-inflammatory photodynamic therapy (PDT) as well as light-emitting-diode (LED) phototherapy were carried out in 20 patients who suffered gunshot wounds and mine-blast injuries to the face, head, and neck. The photodynamic therapy was performed with the use of an aqueous solution of methylene blue at a concentration of 0.1%, the 'Alod-1' infrared laser ('Granat' modification, Russia), and the 'AFS-Solaris' light-emitting diode-based phototherapeutic apparatus (Russia). The analysis of the results of the study has demonstrated the high efficiency of the proposed approach that made it possible to prevent the development of severe septic complications, reduce the amount of drug therapy, significantly shorten duration of the treatment, and create the conditions for the earlier rehabilitation and further plastic and cosmetic restoration of the tissue structures.
本研究的目的是提高耳鼻喉科临床中遇到的面部、头部和颈部枪伤及地雷爆炸伤后果的治疗效果,预防受伤组织中形成大面积分界区,并为这些组织进行进一步的修复治疗做准备。对20例面部、头部和颈部遭受枪伤及地雷爆炸伤的患者进行了抗菌和抗炎光动力疗法(PDT)以及发光二极管(LED)光疗。光动力疗法使用浓度为0.1%的亚甲蓝水溶液、“Alod-1”红外激光(俄罗斯“Granat”改进型)和基于发光二极管的“AFS-Solaris”光疗设备(俄罗斯)进行。对研究结果的分析表明,所提出的方法具有很高的效率,能够预防严重脓毒症并发症的发生,减少药物治疗量,显著缩短治疗时间,并为早期康复以及组织结构的进一步整形和美容修复创造条件。