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[人类中的口疮病毒,智利病例报告予以证实]

[Orf virus in human, confirmation in case report from Chile].

作者信息

Flores Carlos, González Erika, Verna Andrea, Peralta Andrea, Madariaga Carolina, Odeón Anselmo, Cantón Germán

机构信息

Facultad de Ciencias, Universidad Mayor, Santiago, Chile.

Instituto Nacional de Tecnología Agropecuaria, Balcarce, Buenos Aires, Argentina.

出版信息

Rev Chilena Infectol. 2017 Dec;34(6):607-609. doi: 10.4067/S0716-10182017000600607.

DOI:10.4067/S0716-10182017000600607
PMID:29488558
Abstract

Infection with the orf virus, also known as contagious ecthyma, is recognized as an occupational zoonosis worldwide. It is diagnosed by cutaneous lesions that progress rapidly from macules to papules, vesicles and pustules. The clinical case of a student of veterinary medicine who had had contact with goats, clinically healthy and without apparent lesions, which occured 19 days ago, is reported. She presented two vesicular lesions that coalesced to form a larger lesion surrounded by an erythematous halo. The lesions were compatible with the classical presentation of those produced by the orf virus in humans. The presence of the orf virus was confirmed by a nested PCR from biopsy tissue. It is one of the first cases confirmed by molecular techniques in humans in Chile.

摘要

感染口疮病毒,也称为传染性脓疱性皮炎,在全球范围内被认为是一种职业性人畜共患病。它通过皮肤病变进行诊断,这些病变从斑疹迅速发展为丘疹、水疱和脓疱。报告了一名兽医专业学生的临床病例,该学生19天前接触过表面健康且无明显病变的山羊。她出现了两个水疱性病变,融合形成一个更大的病变,周围有红斑晕。这些病变与人类感染口疮病毒后的典型表现相符。通过对活检组织进行巢式PCR确认了口疮病毒的存在。这是智利首例通过分子技术确诊的人类病例。

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1
[Orf virus in human, confirmation in case report from Chile].[人类中的口疮病毒,智利病例报告予以证实]
Rev Chilena Infectol. 2017 Dec;34(6):607-609. doi: 10.4067/S0716-10182017000600607.
2
Multifocal cutaneous ORF virus infection in goats in the Amazon region, Brazil.巴西亚马逊地区山羊多灶性皮肤口疮病毒感染。
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Pathogenicity of blood orf virus isolates in the development of dairy goat contagious pustular dermatitis.血液口疮病毒分离株在山羊传染性脓疱性皮炎发病中的致病性。
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Genetic characterization of orf virus associated with an outbreak of severe orf in goats at a farm in Lusaka, Zambia (2015).赞比亚卢萨卡一个农场山羊严重口疮暴发相关口疮病毒的基因特征分析(2015年)
Arch Virol. 2017 Aug;162(8):2363-2367. doi: 10.1007/s00705-017-3352-y. Epub 2017 Apr 4.
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[Histopathology of Orf].[羊痘疮组织病理学]
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Evaluation of homologous and heterologous protection induced by a virulent field strain of orf virus and an orf vaccine in goats.评估羊痘病毒强毒株和一种羊痘疫苗在山羊中诱导的同源和异源保护作用。
Am J Vet Res. 2012 Jan;73(1):86-90. doi: 10.2460/ajvr.73.1.86.
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A viral infection of the hand commonly seen after the feast of sacrifice: human orf (orf of the hand).在宰牲节盛宴后常见的手部病毒感染:人类传染性软疣(手部传染性软疣)
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Drastic cutaneous multi-focal orf infection in goats, causing severe dysfunctioning.山羊严重的皮肤多灶性羊痘感染,导致严重功能障碍。
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Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia.埃塞俄比亚西北部小反刍动物传染性脓疱病(口疮病毒)的分子鉴定与研究
BMC Vet Res. 2018 Jan 15;14(1):13. doi: 10.1186/s12917-018-1339-x.

引用本文的文献

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Orf, a Human Parapoxvirus Infection.羊口疮,一种人类副痘病毒感染。
Adv Exp Med Biol. 2024;1451:171-181. doi: 10.1007/978-3-031-57165-7_11.
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Orf Infection on the Scalp of a Taiwanese Woman: A Case Report and Literature Review.一名台湾女性头皮的羊痘感染:病例报告及文献综述
Life (Basel). 2023 Jan 28;13(2):358. doi: 10.3390/life13020358.
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Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades.过去二十年副痘病毒的基因组特征与进化
Pathogens. 2020 Oct 27;9(11):888. doi: 10.3390/pathogens9110888.
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Outbreak of contagious ecthyma caused by Orf virus (Parapoxvirus ovis) in a vaccinated sheep flock in Uruguay.乌拉圭接种疫苗羊群爆发传染性脓疱性皮炎(羊口疮病毒)。
Braz J Microbiol. 2019 Apr;50(2):565-569. doi: 10.1007/s42770-019-00057-7. Epub 2019 Mar 5.