Castaño-Jaramillo Lina María, Beltrán-Arroyave C, Santander-Peláez L C, Vélez-Escobar A M, Garcés-Samudio C G, Trujillo-Honeysberg Mónica
Universidad CES, Medellín, Colombia.
Universidad de Antioquia, Colombia.
Rev Chilena Infectol. 2017 Oct;34(5):487-490. doi: 10.4067/S0716-10182017000500487.
Skin and soft tissue infections (SSTI) are very common in children and Staphylococcus aureus is the main agent, with an increase of methicillin resistant strains (MRSA) in recent years.
To identify the frequency of MRSA in skin and soft tissue infections (SSTI) in children from a high complex hospital in Medellin, Colombia.
This is a descriptive, retrospective study, information was obtained from medical records. We included patients younger than 18 years with SSTI due to S. aureus who did not meet criteria for invasive disease.
The prevalence of MRSA in this population was 31%. The main diagnosis was cutaneous abscess (68%), followed by surgical site infection (15%) and non-purulent cellulitis (6%). Eighty five percent of the patients had at least 1 comorbidity. All isolates were sensitive to rifampicin and cotrimoxazole and 8% of the isolates were resistant to clindamycin. There was a higher prevalence of MRSA in patients under 2 years compared to older (60 vs 23%, p = 0,0109).
In view of the high prevalence of MRSA in SSTI, empirical treatment with adequate coverage for MRSA is recommended, especially for patients under 2 years of age.
皮肤和软组织感染（SSTI）在儿童中非常常见，金黄色葡萄球菌是主要病原体，近年来耐甲氧西林菌株（MRSA）有所增加。
确定哥伦比亚麦德林一家高复杂性医院儿童皮肤和软组织感染（SSTI）中MRSA的发生率。
这是一项描述性回顾性研究，从病历中获取信息。我们纳入了年龄小于18岁、因金黄色葡萄球菌导致SSTI且不符合侵袭性疾病标准的患者。
该人群中MRSA的患病率为31%。主要诊断为皮肤脓肿（68%），其次是手术部位感染（15%）和非化脓性蜂窝织炎（6%）。85%的患者至少有一种合并症。所有分离株对利福平和复方新诺明敏感，8%的分离株对克林霉素耐药。2岁以下患者中MRSA的患病率高于年龄较大者（60%对23%，p = 0.0109）。
鉴于SSTI中MRSA的高患病率，建议对MRSA进行充分覆盖的经验性治疗，尤其是对于2岁以下的患者。
