Casado-Verrier Beatriz, Gómez-Fernández Cristina, Paño-Pardo José Ramón, Gómez-Gil Rosa, Mingorance-Cruz Jesús, Moreno-Alonso de Celada Ricardo, Herranz-Pinto Pedro
Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.
Enferm Infecc Microbiol Clin. 2012 Jun;30(6):300-6. doi: 10.1016/j.eimc.2011.11.011. Epub 2012 Jan 18.
Since it was first described in the 1990s, Methicillin-Resistant Staphylococcus aureus infection among people with no contact with a hospital setting or with no traditional risk factors, has spread worldwide and is now an important epidemiological and public health problem.
The present prospective and observational study was carried out from April to November 2010. All adult patients with community-acquired suppurative skin and soft tissue infection (SSTI) attending the Emergency Department were enrolled. Clinical, microbiological and epidemiological features of the infection were assessed.
A total of 59 samples were collected from 59 patients and CA-MRSA was isolated in 13 of them. Prevalence of CA-MRSA in patients with suppurative SSTI seen in the emergency department was 22.03%, and was 33.3% in patients with staphylococcal infection. Is worth noting the greater presence of necrosis detected in CA-MRSA lesions. Only 3 patients required hospital admission. Eleven of the 13 strains were Panton-Valentine leucocidin producers, and 5 were resistant to non-betalactam antibiotics. CA MRSA infection is still more frequent in the immigrant population.
Data on CA-MRSA prevalence in Spain are sparse. This study aims to emphasise the current importance of this emergent pathogen in our area. About one third of suppurative staphylococcal SSTI presenting in our emergency department are caused by this agent, confirming a rapid spread in our country. Some clinical features, such as the high presence of necrosis, are closely related to CA-MRSA.
自20世纪90年代首次被描述以来，在没有医院接触史或没有传统危险因素的人群中，耐甲氧西林金黄色葡萄球菌感染已在全球范围内传播，如今已成为一个重要的流行病学和公共卫生问题。
本前瞻性观察性研究于2010年4月至11月进行。纳入了所有到急诊科就诊的社区获得性化脓性皮肤和软组织感染（SSTI）的成年患者。对感染的临床、微生物学和流行病学特征进行了评估。
共从59例患者中采集了59份样本，其中13份分离出社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）。在急诊科就诊的化脓性SSTI患者中，CA-MRSA的患病率为22.03%，在葡萄球菌感染患者中为33.3%。值得注意的是，在CA-MRSA病变中检测到更多的坏死情况。只有3例患者需要住院治疗。13株菌株中有11株产生杀白细胞素，5株对非β-内酰胺类抗生素耐药。CA-MRSA感染在移民人群中仍然更为常见。
西班牙关于CA-MRSA患病率的数据很少。本研究旨在强调这种新兴病原体在我们地区当前的重要性。在我们急诊科出现的化脓性葡萄球菌SSTI中，约三分之一是由这种病原体引起的，证实了其在我国的快速传播。一些临床特征，如坏死的高发生率，与CA-MRSA密切相关。
