Han Fang, Gao Lu, Wang Yin, Jin Yingying, Lv Yi, Yao Zhenwei, Zhang Jiawen
Department of Radiology Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Medicine (Baltimore). 2018 Mar;97(9):e9745. doi: 10.1097/MD.0000000000009745.
The aim of this study was to explore x-ray computed tomography (CT) and magnetic resonance imaging (MRI) characteristics specific to granular cell tumors (GCTs) of the neurohypophysis.The clinical and imaging data of 6 patients with operation-proven GCTs of the neurohypophysis were analyzed retrospectively.There were 6 patients with GCTs of the neurohypophysis confirmed pathologically. Five of the tumors were purely suprasellar lesions distinct from the intrasellar pituitary gland. One tumor was both intra- and suprasellar. Solid tumors were hyperattenuated and enhanced homogeneously on CT, while showing isointensity on T1WI and heterogeneous hypointensity on T2WI, with homogeneous (4/5) or inhomogeneous (1/5) enhancement. The cystic tumor showed hypointensity on T1WI and hyperintensity on T2WI, with ring enhancement. "Star-like crack sign" was seen in 2 larger solid cases. Calcification was absent in all cases.Well-circumscribed intra and/or suprasellar masses, hyperattenuated and homogeneously enhancing on CT, hypointensity on T2WI, rarely seen calcification, should arouse suspicion of GCTs of the neurohypophysis.
本研究的目的是探讨神经垂体颗粒细胞瘤（GCTs）的X线计算机断层扫描（CT）和磁共振成像（MRI）特征。回顾性分析6例经手术证实的神经垂体GCTs患者的临床和影像资料。有6例经病理证实为神经垂体GCTs。其中5例肿瘤为单纯鞍上病变，与鞍内垂体不同。1例肿瘤同时累及鞍内和鞍上。实性肿瘤在CT上呈高密度且均匀强化，在T1WI上呈等信号，在T2WI上呈不均匀低信号，强化均匀（4/5）或不均匀（1/5）。囊性肿瘤在T1WI上呈低信号，在T2WI上呈高信号，呈环形强化。2例较大实性病例可见“星状裂纹征”。所有病例均无钙化。鞍内和/或鞍上边界清晰的肿块，CT上呈高密度且均匀强化，T2WI上呈低信号，少见钙化，应怀疑为神经垂体GCTs。
