Department of Biology and Medical Parasitology, Pomeranian Medical University in Szczecin, Powstanców Wielkopolskich 72, 70-111, Szczecin, Poland.
Department of Obstetrical and Gynecological Nursing, Pomeranian Medical University, Żołnierska 48, 71-210, Szczecin, Poland.
Environ Geochem Health. 2018 Aug;40(4):1683-1695. doi: 10.1007/s10653-018-0081-4. Epub 2018 Feb 28.
The aim of the study was to evaluate Hg and Se concentrations and Se:Hg molar ratios in the placenta, umbilical cord and fetal membranes, and to examine the relationship between the concentrations of the elements and selected factors. The study material consisted of the placenta, umbilical cord and fetal membranes obtained from 91 healthy women from northwestern and central Poland. In our study mean Hg and Se concentrations in afterbirth were ~ 0.01 mg/kg dry weight (dw) and ≤ 0.5 mg/kg dw, respectively. Correlation analysis showed negative relationships between placenta weight and Se concentration in the placenta and umbilical cord, as well as between placenta length and Se levels in the umbilical cord. We found negative correlations between THg concentration in the placenta and birth weight and between Se concentration in the placenta and umbilical cord and the morphological parameters of the placenta. Furthermore, we noted new types of interactions in specific parts of the afterbirth. In our study, Se:THg molar ratios ranged from 5 to 626; these values indicate protection against Hg toxicity.
本研究旨在评估胎盘、脐带和胎膜中汞 (Hg) 和硒 (Se) 的浓度以及 Se:Hg 摩尔比，并探讨这些元素的浓度与选定因素之间的关系。研究材料由来自波兰西北部和中部的 91 名健康女性的胎盘、脐带和胎膜组成。在我们的研究中，胎盘中 Hg 和 Se 的平均浓度分别约为 0.01 毫克/公斤干重 (dw) 和 ≤0.5 毫克/公斤 dw。相关性分析表明，胎盘重量与胎盘和脐带中 Se 浓度之间、胎盘长度与脐带中 Se 水平之间呈负相关关系。我们发现胎盘中总汞 (THg) 浓度与出生体重之间以及胎盘中 Se 浓度与脐带之间呈负相关关系，并且与胎盘的形态参数之间也呈负相关关系。此外，我们还注意到了胎盘中特定部位存在新的相互作用类型。在本研究中，Se:THg 摩尔比范围为 5 至 626；这些值表明对 Hg 毒性具有保护作用。
