Halsey J H, McDowell H A, Gelman S
Stroke. 1986 Nov-Dec;17(6):1206-8. doi: 10.1161/01.str.17.6.1206.
In eight patients undergoing carotid endarterectomy, the mean velocity and an index of pulse amplitude in the middle cerebral artery were monitored continuously by transcranial doppler ultrasound. rCBF was measured by intracarotid injection of 133 Xenon shortly before and at the time of the carotid artery occlusion, and again a few minutes after carotid flow was reestablished. Comparison of the mean velocity in the MCA and the cortical convexity rCBF revealed relatively little hysteresis in their relationship from prior to after the occlusion. There was however, considerable variability in this relationship among patients. Both the rCBF and the velocity decreased substantially at occlusion in three cases, neither changed very much in three. While in two, though the rCBF decreased significantly, the velocity did not change. The index of pulse amplitude was somewhat more sensitive to the occlusion, decreasing in the seven cases in which it was recorded, including one in which the rCBF did not change.
在8例接受颈动脉内膜切除术的患者中，通过经颅多普勒超声连续监测大脑中动脉的平均流速和脉搏振幅指数。在颈动脉闭塞前不久和闭塞时，通过颈内动脉注射133氙测量局部脑血流量（rCBF），并且在颈动脉血流重建几分钟后再次测量。比较大脑中动脉（MCA）的平均流速和皮质凸面rCBF发现，从闭塞前到闭塞后它们之间的关系中滞后相对较小。然而，患者之间这种关系存在相当大的变异性。在3例中，闭塞时rCBF和流速均大幅下降，3例中两者变化不大。在2例中，虽然rCBF显著下降，但流速没有变化。脉搏振幅指数对闭塞更为敏感，在所记录的7例中均下降，其中1例rCBF未变化。
