Hall Nathan C, Ruutiainen Alexander T
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Diagnostic Imaging, Nuclear Medicine, Corporal Michael J. Crescenz VA Medical Center, 3900 Woodland Avenue, Philadelphia, PA 19104, USA; Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center, 410 West 10th Avenue, Columbus, OH 43210, USA.
Diagnostic Radiology, Corporal Michael J. Crescenz VA Medical Center, 3900 Woodland Avenue, Philadelphia, PA 19104, USA.
Surg Oncol Clin N Am. 2018 Apr;27(2):289-302. doi: 10.1016/j.soc.2017.11.004. Epub 2018 Jan 20.
Progressive technological advancements in imaging have significantly improved the preoperative sensitivity for the detection of very small foci of regionally- or hematogenously-metastatic colorectal cancer. Unfortunately, this information has not translated to continued linear gains in patient survival, and might even result in the false-positive upstaging of some cases: these are two conundrums in the imaging of colorectal cancer. Both conundrums might be resolved by the widespread use of real-time imaging guidance during operative procedures. This might open the way for the widespread use of fluorodeoxyglucose PET/CT for the initial staging of patients with colorectal cancer.
成像技术的不断进步显著提高了术前检测局部或血行转移的极小病灶的结直肠癌的敏感性。不幸的是，这些信息并未转化为患者生存率的持续线性提高，甚至可能导致一些病例出现假阳性分期上调：这是结直肠癌成像中的两个难题。这两个难题都可能通过在手术过程中广泛使用实时成像引导来解决。这可能为氟脱氧葡萄糖PET/CT在结直肠癌患者初始分期中的广泛应用开辟道路。
