Unterbuchner C, Blobner M
Klinik für Anaesthesiologie, Universitätsklinikum Regensburg, Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93051, Regensburg, Deutschland.
Klinik für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München, München, Deutschland.
Anaesthesist. 2018 Mar;67(3):165-176. doi: 10.1007/s00101-018-0425-6.
Neuromuscular blockade (TOF count = 0) can improve tracheal intubation and microlaryngeal surgery. It is also frequently used in many surgical fields including both nonlaparoscopic and laparoscopic surgery to improve surgical conditions and to prevent sudden muscle contractions. Currently there is a controversy regarding the need and the clinical benefits of deep neuromuscular blockade for different surgical procedures. Deep neuromuscular relaxation improves laparoscopic surgical space conditions only marginally when using low intra-abdominal pressure. There is no outcome-relevant advantage of low compared to higher intra-abdominal pressures, but worsen the surgical conditions. Postoperative, residual curarisation can be avoided by algorithm-based pharmacological reversing and quantitative neuromuscular monitoring.
神经肌肉阻滞(四个成串刺激计数 = 0)可改善气管插管和显微喉镜手术。它也常用于包括非腹腔镜和腹腔镜手术在内的许多外科领域,以改善手术条件并防止肌肉突然收缩。目前,对于不同外科手术中深度神经肌肉阻滞的必要性和临床益处存在争议。在使用低腹内压时,深度神经肌肉松弛仅能略微改善腹腔镜手术空间条件。与较高腹内压相比,低腹内压并无与预后相关的优势,反而会使手术条件恶化。术后,通过基于算法的药物逆转和定量神经肌肉监测可避免残余肌松作用。