Hwang Andrew, Iskandar Andrew, Del Rosario Michael, Dasanu Constantin A
1 Department of Medicine, Eisenhower Medical Center, Rancho Mirage, USA.
2 Lucy Curci Cancer Center, Eisenhower Medical Center, Rancho Mirage, USA.
J Oncol Pharm Pract. 2019 Jun;25(4):972-974. doi: 10.1177/1078155218761799. Epub 2018 Mar 2.
Imatinib mesylate is a tyrosine kinase inhibitor used in the treatment of several malignancies. Its use, however, is associated with a number of toxic effects including adverse cutaneous reactions. Herein, we present a case of facial cystic acne in a patient receiving imatinib therapy for chronic myelocytic leukemia. This side effect resolved with cessation of therapy. To the best of our knowledge, this clinical entity has never been previously reported in the medical literature.
甲磺酸伊马替尼是一种用于治疗多种恶性肿瘤的酪氨酸激酶抑制剂。然而，其使用与包括皮肤不良反应在内的多种毒性作用相关。在此，我们报告一例接受伊马替尼治疗慢性粒细胞白血病的患者发生面部囊性痤疮的病例。这种副作用在停止治疗后得到缓解。据我们所知，这一临床情况此前从未在医学文献中报道过。
