用于吸附生物碱的 Fe₃O₄ 纳米粒子的修饰和表征。

Modification and Characterization of Fe₃O₄ Nanoparticles for Use in Adsorption of Alkaloids.

机构信息

College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China.

Guangxi Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Chemical and Pharmaceutical College of Guangxi Normal University, Guilin 541004, China.

出版信息

Molecules. 2018 Mar 2;23(3):562. doi: 10.3390/molecules23030562.

Magnetite (Fe₃O₄) is a ferromagnetic iron oxide of both Fe(II) and Fe(III), prepared by FeCl₂ and FeCl₃. XRD was used for the confirmation of Fe₃O₄. Via the modification of Tetraethyl orthosilicate (TEOS), (3-Aminopropyl)trimethoxysilane (APTMS), and Alginate (AA), Fe₃O₄@SiO₂, Fe₃O₄@SiO₂-NH₂, and Fe₃O₄@SiO₂-NH₂-AA nanoparticles could be obtained, and IR and SEM were used for the characterizations. Alkaloid adsorption experiments exhibited that, as for Palmatine and Berberine, the most adsorption could be obtained at pH 8 when the adsorption time was 6 min. The adsorption percentage of Palmatine was 22.2%, and the adsorption percentage of Berberine was 23.6% at pH 8. Considering the effect of adsorption time on liquid phase system, the adsorption conditions of 8 min has been chosen when pH 7 was used. The adsorption percentage of Palmatine was 8.67%, and the adsorption percentage of Berberine was 7.25%. Considering the above conditions, pH 8 and the adsorption time of 8min could be chosen for further uses.

磁铁矿（Fe₃O₄）是一种具有亚铁（Fe(II)）和铁（Fe(III)）的铁磁性氧化铁，由 FeCl₂ 和 FeCl₃ 制备。XRD 用于确认 Fe₃O₄。通过 Tetraethyl orthosilicate (TEOS)、(3-Aminopropyl)trimethoxysilane (APTMS) 和 Alginate (AA) 的修饰，可以得到 Fe₃O₄@SiO₂、Fe₃O₄@SiO₂-NH₂ 和 Fe₃O₄@SiO₂-NH₂-AA 纳米粒子，并通过 IR 和 SEM 进行了表征。生物碱吸附实验表明，对于巴马汀和小檗碱，在吸附时间为 6 分钟时，在 pH 8 时可以获得最大吸附。在 pH 8 时，巴马汀的吸附率为 22.2%，小檗碱的吸附率为 23.6%。考虑到吸附时间对液相体系的影响，当 pH 为 7 时，选择了 8 分钟的吸附条件。巴马汀的吸附率为 8.67%，小檗碱的吸附率为 7.25%。考虑到上述条件，可以选择 pH 8 和 8min 的吸附时间进行进一步使用。