Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.
Dermatol Clin. 2018 Apr;36(2):135-150. doi: 10.1016/j.det.2017.11.009. Epub 2017 Dec 21.
Papulopustular rosacea is characterized by papules and pustules in the central facial region. We review the literature surrounding the treatment of papulopustular rosacea. PubMed, EMBASE, and Cochrane (Central) databases searches of articles published from 1980 to 2015 were performed using the MeSH terms or keywords "rosacea" and "clinical trial." Additional searches were performed to include rosacea and each treatment modality used. Topical metronidazole, azelaic acid, ivermectin, and oral doxycycline have the most robust data to support their use. Variation in assessment tools and a lack of clinical trial standardization makes comparison of therapeutic options difficult.
脓疱性酒渣鼻的特征为中央面区的丘疹和脓疱。我们对脓疱性酒渣鼻的治疗相关文献进行了回顾。检索了 1980 年至 2015 年发表的文章，使用的 MeSH 术语或关键词为“酒渣鼻”和“临床试验”，并在随后的搜索中纳入了酒渣鼻和每种治疗方法。局部甲硝唑、壬二酸、伊维菌素和口服多西环素的数据最充分，支持其使用。评估工具的差异和临床试验标准化的缺乏使得治疗选择的比较变得困难。
