Preisz Klaudia, Kárpáti Sarolta
Semmelweis Egyetem, Altalános Orvostudományi Kar Bor-, Nemikórtani és Boronkológiai Klinika, Budapest.
Orv Hetil. 2010 Jul 25;151(30):1209-14. doi: 10.1556/OH.2010.28885.
Rosacea is one of the most common chronic dermatological diseases. It is characterized by transient or persistent facial erythema, teleangiectasias, papules and pustules, usually on the central portion of the face. Rosacea can be classified into four main subtypes: erythemato-teleangiectatic, papulopustular, phymatous, and ocular. These subtypes require different therapeutic approaches. Regarding to the pathomechanism, several hypotheses have been documented in the literature, including genetic and environmental factors, vascular abnormalities, dermal matrix degeneration, microorganisms such as Demodex folliculorum and Helicobacter pylori, but the cause of rosacea is still not known. Authors in this article review current literature on new classification system of rosacea, as well as the main pathogenetic theories and current therapeutic options.
酒渣鼻是最常见的慢性皮肤病之一。其特征为面部出现短暂或持续的红斑、毛细血管扩张、丘疹和脓疱,通常出现在面部中央部位。酒渣鼻可分为四种主要亚型:红斑毛细血管扩张型、丘疹脓疱型、鼻赘型和眼型。这些亚型需要不同的治疗方法。关于发病机制,文献中已记录了几种假说,包括遗传和环境因素、血管异常、真皮基质退化、毛囊蠕形螨和幽门螺杆菌等微生物,但酒渣鼻的病因仍不清楚。本文的作者回顾了关于酒渣鼻新分类系统、主要发病理论和当前治疗选择的现有文献。