Dipartimento di Medicina Clinica e Sperimentale, University of Pisa, Italy. Electronic address: liliana.dell'
Dipartimento di Medicina Clinica e Sperimentale, University of Pisa, Italy.
Compr Psychiatry. 2018 May;83:7-11. doi: 10.1016/j.comppsych.2018.01.002. Epub 2018 Jan 5.
Despite discrete autism-related dimensions, such as deficits in communication, empathy and mentalizing are likely to affect the development of personality and despite they actually frequently occur in borderline patients, no research has so far investigated the relationship between autistic traits and Borderline Personality Disorder (BPD). The objective of this study is to investigate the clinical significance of autistic traits in subjects with BPD.
The sample included 50 patients with a clinical diagnosis of BPD and 69 healthy controls. The Structured Clinical Interview for DSM-5 Clinician Version was used to establish the presence of comorbid mental disorders among BPD subjects and to confirm the absence of lifetime mental disorders in the control group. Participants were also asked to fill three self-report instruments: the Adult Autism Subthreshold Spectrum (AdAS Spectrum), the Autism Spectrum Quotient (AQ) and the Mood Spectrum Self-Report (MOODS-SR).
Patients with BPD reported higher autistic traits than healthy individuals. Moreover, autistic traits were shown to exert a significant impact on some clinical features and associated manifestation of BPD, such as suicidality and lifetime exposure to physical and/or sexual abuse.
Subthreshold autism spectrum may be relevant for subjects suffering from BPD and future research may further address clinical correlates of autistic traits among patients with this disorder.
尽管自闭症相关的离散维度，如沟通障碍、同理心和心理理论，可能会影响人格的发展，而且它们实际上经常出现在边缘型人格障碍患者中，但迄今为止，还没有研究调查自闭症特征与边缘型人格障碍（BPD）之间的关系。本研究的目的是调查 BPD 患者自闭症特征的临床意义。
该样本包括 50 名 BPD 临床诊断患者和 69 名健康对照组。使用 DSM-5 临床定式访谈对 BPD 患者的共病精神障碍进行评估，并确认对照组无终生精神障碍。参与者还被要求填写三份自我报告量表：成人自闭症亚临床范围（AdAS 范围）、自闭症特征问卷（AQ）和情绪范围自我报告（MOODS-SR）。
BPD 患者报告的自闭症特征高于健康个体。此外，自闭症特征对 BPD 的一些临床特征和相关表现有显著影响，如自杀倾向和一生中遭受身体和/或性虐待的经历。
亚临床自闭症谱系可能与 BPD 患者有关，未来的研究可能会进一步探讨该障碍患者自闭症特征的临床相关性。
