Cremone Ivan Mirko, Dell'Osso Liliana, Nardi Benedetta, Giovannoni Federico, Parri Francesca, Pronestì Cristiana, Bonelli Chiara, Massimetti Gabriele, Pini Stefano, Carpita Barbara
Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Brain Sci. 2024 Dec 23;14(12):1297. doi: 10.3390/brainsci14121297.
BACKGROUND/OBJECTIVES: Recent research has explored the presence of subthreshold autistic traits (ATs) in individuals with borderline personality disorder (BPD), suggesting that these traits may contribute to the severity of BPD symptoms and increase the risk of other mental health issues, including suicidal behaviors. This study aims to investigate the relationship between ATs and affective symptoms, such as mood instability and suicidality, in people diagnosed with BPD.
A total of 48 subjects with BPD were assessed with self-report questionnaires including the Adult Autism Subthreshold Spectrum (AdAS Spectrum), the mood spectrum self-report version (MOODS-SR) and the ruminative response scale (RRS).
Subjects with significant ATs scored higher than BPD subjects in all domains and in the total score of AdAS Spectrum, RRS, and MOODS-SR, as well as in the items investigating suicidality. RRS total score, its depression domain, and the MOODS-SR rhythmicity domain, as well as suicidality, were predictors of the presence of ATs.
Our data confirm the relationship between the presence of clinically significant ATs and affective symptoms, ruminative thinking, and suicidality in patients with BPD.
背景/目的:最近的研究探讨了边缘性人格障碍(BPD)患者中亚阈值自闭症特质(ATs)的存在情况,表明这些特质可能导致BPD症状的严重程度增加,并增加包括自杀行为在内的其他心理健康问题的风险。本研究旨在调查被诊断为BPD的人群中ATs与情感症状(如情绪不稳定和自杀倾向)之间的关系。
共有48名BPD患者通过自我报告问卷进行评估,这些问卷包括成人自闭症亚阈值谱(AdAS Spectrum)、情绪谱自我报告版(MOODS-SR)和反刍反应量表(RRS)。
具有显著ATs的受试者在AdAS Spectrum、RRS和MOODS-SR的所有领域、总分以及调查自杀倾向的项目中的得分均高于BPD受试者。RRS总分、其抑郁领域、MOODS-SR节律领域以及自杀倾向是ATs存在的预测因素。
我们的数据证实了BPD患者中具有临床意义的ATs的存在与情感症状、反刍思维和自杀倾向之间的关系。