Thomas N P, Turner I G, Jones C B
J Bone Joint Surg Br. 1987 Mar;69(2):312-6. doi: 10.1302/0301-620X.69B2.2950103.
Four types of prosthetic replacement for the anterior cruciate ligament (carbon fibre, carbon fibre and Dacron composite, Dacron alone and bovine xenograft) were assessed at three, six and 12 months after implantation in the knees of New Zealand white rabbits. The synovium and both intra-articular and intra-osseous portions of the ligaments were examined macroscopically, by light microscopy and by scanning electron microscopy. All the knees showed mild synovitis, and there was no significant growth into the intra-articular part of any ligament. Carbon fibre and xenograft did not appear to be suitable materials in this animal model. The composite ligament showed short-term ingrowth of fibrous tissue only into the periphery of the sheath in its intra-osseous portion, whereas the Dacron ligament showed progressive fibrous tissue ingrowth with some bony incorporation of its outer fibres.
在新西兰白兔的膝关节中植入前交叉韧带的四种假体替代物（碳纤维、碳纤维与涤纶复合材料、单纯涤纶和牛异种移植物），并在植入后3个月、6个月和12个月进行评估。通过大体观察、光学显微镜和扫描电子显微镜检查滑膜以及韧带的关节内和骨内部分。所有膝关节均表现为轻度滑膜炎，且任何韧带的关节内部分均无明显生长。在该动物模型中，碳纤维和异种移植物似乎不是合适的材料。复合韧带仅在其骨内部分的鞘管周边显示纤维组织的短期长入，而涤纶韧带则显示纤维组织逐渐长入，其外层纤维有一些骨融合。
