基于 ITO/APTES/ErGO 电极电化学检测酪胺及其在实际样品分析中的应用。
Electrochemical detection of tyramine with ITO/APTES/ErGO electrode and its application in real sample analysis.
机构信息
College of Chemistry and Chemical Engineering, Key Laboratory of Natural Medicine and Immune-Engineering of Henan Province, Henan University, Kaifeng 475004, China; Dept. of Chemical Engineering, Jessore University of Science and Technology, Jessore 7408, Bangladesh.
College of Chemistry and Chemical Engineering, Key Laboratory of Natural Medicine and Immune-Engineering of Henan Province, Henan University, Kaifeng 475004, China.
出版信息
Biosens Bioelectron. 2018 Jun 15;108:76-81. doi: 10.1016/j.bios.2018.02.042. Epub 2018 Feb 23.
This work reports the development of a simple and cost-effective electrochemical sensor based on electrochemically reduced graphene oxide (ErGO) bound to the surface of indium tin oxide (ITO) electrode through 3-aminopropyltriethoxysilane (APTES) monolayer (ITO/APTES/ErGO) for selective and sensitive detection of tyramine. The features of the modified electrode were studied by scanning electron microscopy (SEM), cyclic voltammetry (CV), and electrochemical impedance (EIS) methods. The analytical performance of the developed sensor was evaluated with respect to linear detection range, limit of detection, stability, coexistence interference and reproducibility. The modified device exhibited electrocatalytic activity toward tyramine oxidation within two linear concentration range of 1-100 nM, and 1-100 µM, with LOD of 0.1 nM. Finally, the sensor successfully detected tyramine in commercially available real samples with satisfactory recovery ranges. The proposed modified sensor offers distinct advantages including low cost, simple handling, good sensitivity and high selectivity.
这项工作报道了一种简单且经济高效的电化学传感器的开发，该传感器基于通过 3-氨丙基三乙氧基硅烷（APTES）单层将电化学还原的氧化石墨烯（ErGO）结合到氧化铟锡（ITO）电极表面上（ITO/APTES/ErGO），用于对酪胺进行选择性和灵敏检测。通过扫描电子显微镜（SEM）、循环伏安法（CV）和电化学阻抗（EIS）方法研究了修饰电极的特性。针对线性检测范围、检测限、稳定性、共存干扰和重现性，评估了开发的传感器的分析性能。该修饰器件对酪胺氧化具有电催化活性，在 1-100 nM 和 1-100 µM 的两个线性浓度范围内，检测限为 0.1 nM。最后，该传感器成功地用商业上可获得的实际样品进行了酪胺检测，具有令人满意的回收率范围。所提出的修饰传感器具有成本低、操作简单、灵敏度高和选择性好等优点。
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