Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Anal Chim Acta. 2018 Jul 12;1013:63-70. doi: 10.1016/j.aca.2018.01.049. Epub 2018 Feb 10.
The various synthetic routes of carbon dots (C-dots) feature a considerable step toward their potential use in chemical sensors and biotechnology. Herein, by coupling phosphorus and nitrogen element introduction, the adenosine-derived N/P co-doped C-dots with fluorescence enhancement were achieved. By separately employing adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine-5'-triphosphate as precursors, the effect of N/P co-doping on the fluorescence emission is discussed in detail. The formed C-dots with adenosine monophosphate exhibited strong blue fluorescence with a high quantum yield of 33.81%. Then the C-dots were employed as a fluorescent probe and utilized to develop a fast, sensitive, and selective picric acid sensor. The fluorescence of C-dots can be quenched by picric acid immediately, giving rise to a picric acid determination down to 30 nM. The possible mechanism of fluorescence quenching was discussed, which was proved to be inner filter effect and static quenching. Moreover, this method has the potential to detect picric acid in environmental water samples.
各种合成碳点 (C-dots) 的途径为其在化学传感器和生物技术中的潜在应用提供了重要的一步。在此，通过引入磷和氮元素的偶联，实现了荧光增强的腺苷衍生的 N/P 共掺杂 C-dots。分别以腺苷、单磷酸腺苷、二磷酸腺苷和 5'-三磷酸腺苷作为前体，详细讨论了 N/P 共掺杂对荧光发射的影响。以单磷酸腺苷为前体制得的 C-dots 表现出强烈的蓝色荧光，量子产率高达 33.81%。然后，将 C-dots 用作荧光探针，并用于开发快速、灵敏和选择性的苦味酸传感器。苦味酸可以立即猝灭 C-dots 的荧光，从而可以检测到低至 30 nM 的苦味酸。讨论了荧光猝灭的可能机制，证明是内滤效应和静态猝灭。此外，该方法有望检测环境水样中的苦味酸。
