Department of Gynecologic Oncology, University of Palermo, Palermo, Italy.
Department of Woman and Child Health, Catholic University of the Sacred Heart, Rome, Italy.
J Minim Invasive Gynecol. 2018 Nov-Dec;25(7):1217-1223. doi: 10.1016/j.jmig.2018.02.015. Epub 2018 Mar 2.
To evaluate the clinical presentation and surgical outcome in patients with deep lateral pelvic endometriosis (dLPE).
A retrospective multicentric study (Canadian Task Force classification II-2).
University tertiary referral centers.
One hundred forty-eight women with deep infiltrating endometriosis (DIE).
Laparoscopic excision of DIE. Disease distribution was classified as follows: central pelvic endometriosis (CPE) when DIE involved 1 of the following anatomic sites: cervix, vagina, uterosacral ligaments, rectum, bladder, or pelvic peritoneum; superficial lateral pelvic endometriosis when parametria, ureters, or hypogastric plexus were involved; and dLPE in the presence of sacral plexus and/or sciatic nerve infiltration.
All patients showed CPE. LPE was detected in 116 cases (78.4%); among these, we observed dLPE in 41 patients (35.3%). dLPE occurred in 40% of women with CPE and in 72.7% of patients with hypogastric plexus involvement. Thirty women with dLPE (73.2%) received gastrointestinal or urologic resection in addition to gynecologic procedures compared with 40 patients (57.1%) without dLPE (p = .001). No differences were observed in terms of perioperative complications according to the presence of dLPE. According to univariate/multivariate analysis, chronic pelvic pain was the only predictor of dLPE (odds ratio = 3.041, p = .003). The median preoperative visual analog scale for dysmenorrhea (median = 8, range, 0-10) and dyspareunia (median = 5; range, 0-10) dropped to 0 after surgery. The median follow-up was 36 months (range, 6-66 months) with a recurrence rate of 8.8%.
dLPE is not a rare event in women with DIE. Complete laparoscopic removal of endometriosis seems to ensure benefit in terms of recurrence rate without increased surgical morbidities.
评估深部侧盆子宫内膜异位症(dLPE)患者的临床表型和手术结果。
回顾性多中心研究(加拿大任务组分类 II-2)。
大学三级转诊中心。
148 名深部浸润性子宫内膜异位症(DIE)患者。
腹腔镜切除 DIE。疾病分布如下:当 DIE 累及以下解剖部位之一时,为中央盆腔子宫内膜异位症(CPE):宫颈、阴道、子宫骶韧带、直肠、膀胱或盆腔腹膜;当涉及附件、输尿管或腹下丛时,为浅表侧盆子宫内膜异位症;当累及骶丛和/或坐骨神经浸润时,为深部侧盆子宫内膜异位症。
所有患者均表现为 CPE。在 116 例患者(78.4%)中发现 LPE;其中,我们观察到 41 例(35.3%)dLPE。在 40%的 CPE 患者和 72.7%的腹下丛受累患者中发现 dLPE。30 例 dLPE 患者(73.2%)除妇科手术外,还接受胃肠或泌尿科切除术,而 40 例无 dLPE 患者(57.1%)(p = 0.001)。根据有无 dLPE,手术并发症无差异。根据单因素/多因素分析,慢性盆腔疼痛是 dLPE 的唯一预测因素(优势比=3.041,p=0.003)。术前痛经视觉模拟评分中位数(8 分,范围 0-10)和性交痛评分中位数(5 分,范围 0-10)术后降至 0。中位随访时间为 36 个月(6-66 个月),复发率为 8.8%。
dLPE 在患有 DIE 的女性中并不罕见。彻底的腹腔镜切除子宫内膜异位症似乎可以确保复发率的获益,而不会增加手术并发症。