Apaydin Suheyla
University of Health Sciences, Medical Faculty, Internal Medicine, Bakirkoy Dr. Sadi Konuk Training and Research Center, Nephrology Department, Istanbul, Turkey.
Transfus Apher Sci. 2018 Feb;57(1):8-12. doi: 10.1016/j.transci.2018.02.007. Epub 2018 Feb 20.
Therapeutic plasma aphresis (plasmapheresis) is one form of treatment that is frequently used in practice of Nephrology. Plasmapheresis is the most important part of the therapies for Goodpasture's syndrome and anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis which are causes of rapidly progressive glomerulonephritis. The reason why the effectiveness of plasmapheresis therapy cannot be clearly demonstrated in renal involvement in these diseases is that it does not appear to be possible to recruit an adequate number of patients and plasmapheresis is not effective in advanced disease if early treatment is not initiated.
治疗性血浆置换术（血浆置换）是肾脏病学实践中常用的一种治疗方式。血浆置换是治疗肺出血肾炎综合征和抗中性粒细胞胞浆抗体（ANCA）相关性血管炎的最重要治疗手段，这两种疾病是快速进展性肾小球肾炎的病因。血浆置换疗法在这些疾病的肾脏受累方面疗效无法得到明确证实，原因在于似乎难以招募到足够数量的患者，而且如果不早期开始治疗，血浆置换在疾病晚期是无效的。
