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类风湿关节炎患者工作效率与临床特征之间的关系

Relationship Between Work Productivity and Clinical Characteristics in Rheumatoid Arthritis.

作者信息

Salazar-Mejía Carlos Eduardo, Galarza-Delgado Dionicio Ángel, Colunga-Pedraza Iris Jazmín, Azpiri-López José Ramón, Wah-Suárez Martín, Wimer-Castillo Blanca Otilia, Salazar-Sepúlveda Laura Leticia

机构信息

Departamento de Medicina Interna, Hospital Universitario «Dr. José Eleuterio González», Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

Servicio de Reumatología, Departamento de Medicina Interna, Hospital Universitario «Dr. José Eleuterio González», Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

出版信息

Reumatol Clin (Engl Ed). 2019 Nov-Dec;15(6):327-332. doi: 10.1016/j.reuma.2017.12.006. Epub 2018 Mar 2.

Abstract

OBJECTIVE

This study assesses the relationship between the ability to perform productive activities and the clinical characteristics of RA, such as disease activity, quality of life, functional capacity, workload, pharmacotherapy, and comorbidities.

MATERIALS AND METHODS

A cross-sectional, observational and descriptive study was conducted. Patients aged 18-75years with a diagnosis of RA according to ACR/EULAR 2010 criteria who attended regularly to the Rheumatology service in the period between January and March 2017 were included. The questionnaires, WPAI-AR, HAQ-DI and RAQoL, were applied. RA disease activity was measured by DAS28-PCR. Correlations were made between the clinical data obtained and work productivity and activity impairment measured by WPAI-AR.

RESULTS

Two hundred four patients with a diagnosis of RA were included, of whom 92.6% were women. Mean age was 54.46±9.3years. Regarding the percentage of impairment of daily life activities, we found a significant difference between employed and unemployed patients (P≤.002). A positive correlation was found between RA activity measured by DAS28-PCR, quality of life, and functional ability with the percentages of absenteeism, presenteeism, overall productivity loss, and impairment of daily life activities.

CONCLUSION

A correlation between RA disease activity, functional capacity, quality of life, and working impairment was found. The strongest association was established with the degree of functional capacity.

摘要

目的

本研究评估进行生产性活动的能力与类风湿关节炎(RA)临床特征之间的关系,如疾病活动度、生活质量、功能能力、工作量、药物治疗及合并症。

材料与方法

开展一项横断面、观察性和描述性研究。纳入年龄在18 - 75岁之间、根据2010年美国风湿病学会(ACR)/欧洲抗风湿病联盟(EULAR)标准诊断为RA且在2017年1月至3月期间定期到风湿病科就诊的患者。应用了WPAI - AR、HAQ - DI和RAQoL问卷。通过DAS28 - PCR测量RA疾病活动度。对所获得的临床数据与通过WPAI - AR测量的工作生产力和活动受损情况进行相关性分析。

结果

纳入204例诊断为RA的患者,其中92.6%为女性。平均年龄为54.46±9.3岁。关于日常生活活动受损百分比,我们发现就业和未就业患者之间存在显著差异(P≤0.002)。通过DAS28 - PCR测量的RA活动度、生活质量和功能能力与旷工率、出勤主义、总体生产力损失及日常生活活动受损百分比之间存在正相关。

结论

发现RA疾病活动度、功能能力、生活质量与工作受损之间存在相关性。与功能能力程度建立了最强的关联。

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